Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
A new device called the Argus II has been implanted in over 50 patients, many of whom can now see color, movement and objects and researchers have even streamed braille patterns directly into a blind patient's retina, allowing him to read four-letter words accurately and quickly with the ocular neuroprosthetic device.
Argus II uses a small camera mounted on a pair of glasses, a portable processor to translate the signal from the camera into electrical stimulation and a microchip with electrodes implanted directly on the retina.
Cardio3 BioSciences (C3BS) announced it has received authorization from the Belgian Federal Agency for Medicines and Health Products (FAMHP) to begin its Congestive Heart failure Cardiopoietic Regenerative Therapy (CHART-1) European Phase III trial for C3BS-CQR-1 in Belgium. This represents a world premiere for a regenerative medicine product targeting heart failure to be tested in the context of a Phase III trial. C3BS-CQR-1 is an autologous stem cell therapy for heart failure.
It used to be a stereotype that being fat meant you had a happy personality. Then culture went out of its way to vilify fat people and make them miserable - when they weren't vilifying culture or food companies for making people fat.Now researchers claim new genetic evidence about why some people are happier than others - and it involves a gene implicated in obesity. The gene FTO, which is correlated to obesity by the 'being fat is exculpatory' segment of science, has now been similarly associated with an eight percent reduction in the risk of depression. In other words, it's not just an obesity gene but a "happy gene" as well, if your correlation and causation errors roll that way.
Elsevier has launched a new open access, online journal, Leukemia Research Reports. It will publish a range of peer-reviewed short form papers, including brief communications, case reports, letters to the editors, images and debate articles
about basic and/or applied clinical research in leukemias, lymphomas, multiple myeloma and other hematologic malignancies. The editors of Leukemia Research Reports are: Dr Suneel Mundle (Janssen Services LLC and Rush Medical College, Chicago, IL) and Dr Meir Wetzler (State University of New York at Buffalo School of Medicine and Roswell Park Cancer Center, Buffalo, NY).
The All Wales Strategic Medical Group (AWSMG) has approved Zebinix(R) (eslicarbazepine acetate) for the treatment of partial seizures in highly refractory patients who remain uncontrolled with, or are intolerant to, other anti-epileptic medicine combinations.
Eslicarbazepine acetate is licensed in Europe as an adjunctive therapy for adults with partial-onset seizures with or without secondary generalization.
Women scientists in primatology are poorly represented at symposia organized by men, but receive equal representation when symposia organizers are women or mixed groups, according to an analysis published in PLOS ONE.
The authors examined female participation at major scientific conferences for primate scientists and anthropologists, where symposia are largely by invitation but posters and other talks are initiated by participants. They found that within the field of primatology, women give more posters than talks, whereas men give more talks than posters. Their analysis also shows that symposia organized by men on average included half the number of women authors (29%) than symposia organized by women or both men and women (58 to 64%).
While in deep sleep, our hippocampus sends messages to our cortex and changes its plasticity, possibly transferring recently acquired knowledge to long-term memory.
How exactly is this done? Scientists from the Max Planck Institute for Biological Cybernetics have developed a multimodal methodology called "neural event-triggered functional magnetic resonance imaging" (NET-fMRI) and presented the very first results obtained using it in experiments with both anesthetized and awake, behaving monkeys.
The dwarf planet Makemake is about two thirds of the size of Pluto and farther from the Sun - but closer than Eris, the most massive so-called dwarf planet in the Solar System after the confusing reconfiguration by the International Astronomical Union that said Pluto was not a planet but then was, only a special non-planet along with others.
Like Eris, but unlike Pluto, Makemake has no atmosphere, making it even less sensical as a planet.
Researchers have unveiled a new way to use sunlight to produce steam and other vapors without heating an entire container of fluid to the boiling point. The research could lead to inexpensive, compact devices for purification of drinking water, sterilization of medical instruments and sanitizing sewage. Metallic nanoparticles - so small that 1,000 would fit across the width of a human hair - absorb large amounts of light, resulting in a dramatic rise in their temperature. That ability to generate heat has fostered interest among scientists in using nanoparticles in a range of applications. These include photothermal treatment of certain forms of cancer, laser-induced drug release and nanoparticle-enhanced bioimaging.
A new approach to invisibility cloaking goes beyond transformation optics and those tiresome Harry Potter analogies. It is instead for us at sea to shield floating objects, like oil rigs and ships, from rough waves and is based on the influence of the ocean floor's topography on the various "layers" of ocean water.Reza Alam, assistant professor of mechanical engineering at the University of California, Berkeley, will describe at the American Physical Society's (APS) Division of Fluid Dynamics (DFD) meeting how the variation of density in ocean water can be used to cloak floating objects against incident surface waves
Work-hour caps for surgical residents designed to lessen complication rates have not accomplished that. Instead, the period after work-hour limits were introduced saw an uptick in complication rates , according to findings which raise concerns that limiting residents' work hours isn't really a benefit.The analysis was designed to evaluate the patient safety impact of rules limiting the hours worked by residents, a measure introduced in 2003. The goal of the limits, a maximum of 88 hours per week, was to reduce the risk of errors and injury related to resident fatigue.
An international team of researchers has resolved the evolutionary relationships of Necrolestes patagonensis, the so-called “grave robber” because of its burrowing and underground lifestyle. This much-debated fossil mammal from South America has been a paleontological riddle for 121 years but a recent fossil discovery and comparative anatomical analysis helped researchers to correctly place the strange 16-million-year-old Necrolestes, with its upturned snout and large limbs for digging, in the mammal evolutionary tree.