Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
An international team of astronomers has viewed two distinct "tails" found on a long tail of gas that is believed to be forming stars where few stars have been formed before. The new observation was made by the Chandra X-ray Observatory and is detailed in a paper published this month in the Astrophysical Journal.This gas tail was originally spotted by astronomers three years ago using a multitude of telescopes, including NASA's Chandra X-ray Observatory and the Southern Astrophysical Research telescope, a Chilean-based observatory in which MSU is one of the partners. The new observations show a second tail, and a fellow galaxy, ESO 137-002, that also has a tail of hot X-ray-emitting gas.
Researchers from the Max Planck Institute of Biochemistry have obtained 3-D images of the vesicles and filaments involved in communication between neurons. The effort was made possible a novel technique in electron microscopy, which cools cells so quickly that their biological structures can be frozen while fully active."We used electron cryotomography, a new technique in microscopy based on ultra-fast freezing of cells, in order to study and obtain three-dimensional images of synapsis, the cellular structure in which the communication between neurons takes place in the brains of mammals" Rubén Fernández-Busnadiego, lead author of the study, which appears in the Journal of Cell Biology
In a recently released report the National Research Council lays out several options NASA could pursue in order to detect more near-Earth objects (NEOs) – asteroids and comets that could pose a hazard if they cross Earth's orbit. While impacts by large NEOs are rare, a single impact could inflict extreme damage, raising the classic problem of how to confront a possibility that is both very rare and very important. Far more likely are those impacts that cause only moderate damage and few fatalities. Conducting surveys for NEOs and detailed studies of ways to mitigate collisions is best viewed as a form of insurance, the report says. How much to spend on these insurance premiums is a decision that must be made by the nation's policymakers.
Research published in BMC Ecology suggests that genetics may provide valuable clues as to how to crack down on the animal smuggling trade, while also helping to safely reintroduce rescued apes into the wild. The population of chimpanzees across western Africa has decreased by 75% in the past 30 years, due in part to widespread chimp hunting, and new strategies are needed to curb this illegal activity. Researchers have been comparing genetic sequences from rescued chimpanzees with those of their wild counterparts across several areas of the country and its border with Nigeria. In doing so, they hope to determine where the rescued chimps come from and thereby assess whether smuggling was a widespread problem, or if hunting hotspots existed.
2009 was tied for the second warmest year on record, and in the Southern Hemisphere, last year was the warmest on record, according to a new analysis of global surface temperatures by NASA scientists.Although 2008 was the coolest year of the decade because of a strong La Nina that cooled the tropical Pacific Ocean, 2009 saw a return to a near-record global temperatures as the La Nina diminished, according to the new analysis by NASA's Goddard Institute for Space Studies (GISS) in New York. The past year was a small fraction of a degree cooler than 2005, the warmest on record, putting 2009 in a virtual tie with a cluster of other years --1998, 2002, 2003, 2006, and 2007 -- for the second warmest on record.
How does an outfielder get to the right place at the right time to catch a fly ball? According to a recent article in the Journal of Vision, the "outfielder problem" represents the definitive question of visual-motor control. How does the brain use visual information to guide action?To test three theories that might explain an outfielder's ability to catch a fly ball, researchers programmed Brown University's virtual reality lab, the VENLab, to produce realistic balls and simulate catches. The team then lobbed virtual fly balls to a dozen experienced ball players.
Epidemiological studies indicate that obesity comes with an increased risk of developing cancer, and especially certain types such as liver cancer. Now, a group of researchers reporting in Cell say they can explain how obesity acts as a "bona fide tumor promoter."In the paper, researchers show that liver cancer is fostered by the chronic inflammatory state that goes with obesity, and two well known inflammatory factors in particular. The findings suggest that anti-inflammatory drugs that have already been taken by millions of people for diseases including rheumatoid arthritis and Crohn's disease may also reduce the risk of cancer in those at high risk due to obesity and perhaps other factors as well.
The presumption that children need both a mother and a father may be readily accepted by many people today, but there is little evidence to support the idea, say sociologists from USC and NYU. In a new Journal of Marriage and Family study, the team argues that "fatherless" children are not necessarily at a disadvantage and that men do not provide a different set of parenting skills than women.Extending their prior work on gender and family, Timothy Biblarz and Judith Stacey analyzed relevant studies about parenting, including available research on single-mother and single-father households, gay male parents and lesbian parents.
What does it take to stop a deadly bioterrorism attack? A strong military? Secured borders? Good Political leaders? If you chose any of the above, you're wrong. The answer is actually llamas--or their proteins to be exact. According to a new study in PLoS One, single domain antibodies found in llamas (sdAb) may help scientists detect botulinum neurotoxins (BoNTs), substances 100 billion times more toxic than cyanide, which the Centers for Disease Control says pose a potential bioterror threat.
The natural climate archives recorded in a stalagmite from a limestone cave in southern Arizona link the Southwest's winter precipitation to temperatures in the North Atlantic, according to new research in Nature Geoscience. The finding is the first to document that the abrupt changes in Ice Age climate known from Greenland also occurred in the southwestern U.S.The stalagmite yielded an almost continuous, century-by-century climate record spanning 55,000 to 11,000 years ago. During that time ice sheets covered much of North America, and the Southwest was cooler and wetter than it is now.
As people age, they gradually lose their ability to filter out irrelevant information. But that may actually give aging adults a memory advantage over their younger counterparts, according to a new study appearing in Psychological Science.The study demonstrated that when older adults "hyper-encode" extraneous information – and they typically do this without even knowing they're doing it – they have the unique ability to "hyper-bind" the information; essentially tie it to other information that is appearing at the same time.
Some animal-pollinated plants face an interesting dilemma. The same animals they rely on for pollination also like to eat them. This is the case for Nicotiana attenuata, a wild tobacco plant that grows in the American Southwest. The plant is pollinated by the night-active hawkmoth, which after the quib pro quo exchange of pollination for nectar likes to lay its eggs on N. attenuata—eggs that develop into voracious, leaf-eating caterpillars.