A new cancer vaccine platform works by enhancing the ability of the immune system to recognize cancer by leveraging anti-viral memories it already has - due to the COVID-19 pandemic, the worst outbreak of the last 70 years.
In a study published in the March issue of Cortex, researchers used a brain scanner to record the activity in each stage while people were in the process of drawing faces. The researchers found that the captured visual information is stored as a series of locations or action plans to reach those locations. It is as if the brain remembers key locations and then 'connect the dots' with a straight or curved line to achieve the desired image on the page.Participants who had no particular expertise as artists were studied using an MRI scanner to measure levels of oxygen in the brain. They viewed black and white cartoons of faces and were asked to reproduce them using pencil and paper.
The bacterium Escherichia coli is part of the healthy human intestinal flora. However, E. coli also has pathogenic relatives that trigger diarrhea illnesses: enterohemorrhagic E.coli bacteria. During the course of an infection they infest the intestinal mucosa, causing injury in the process, in contrast to benign bacteria.
Researchers from Boston University School of Medicine (BUSM), Boston Medical Center, Harvard University and the Cambridge Health Alliance found that more than 75 percent of emergency responder candidates for fire and ambulance services in Massachusetts are either overweight or obese. The findings in the journal Obesity on March 19 may have significant consequences for public health and safety.
There has been a perception that running has the same metabolic cost per unit of time no matter the speed — in other words, that the energy needed to run a given distance is the same whether sprinting or jogging. Not so, says Karen Steudel, a zoology professor at the University of Wisconsin-Madison. Though sprinting feels more demanding in the short term, the longer time and continued exertion required to cover a set distance at a slower pace were thought to balance out the difference in metabolic cost.
Hurdia victoria was originally described in 1912 as a crustacean-like animal. Now, researchers reveal it to be just one part of a complex and remarkable new animal that has an important story to tell about the origin of the largest group of living animals, the arthropods. The fossil fragments puzzled together come from the famous 505 million year old Burgess Shale, a UNESCO World Heritage Site in British Columbia, Canada. Uppsala researchers Allison Daley and Graham Budd at the Department of Earth Sciences, together with colleagues in Canada and Britain, describe the convoluted history and unique body construction of the newly-reconstructed Hurdia victoria, which would have been a formidable predator in its time.
Where do supernovae come from?It depends on who you ask. Astronomers know they were exploding stars but there was always more to the story. Researchers from the Dark Cosmology Centre at the Niels Bohr Institute, University of Copenhagen and from Queens University, Belfast say dying red supergiant stars can also produce supernovae.
Want to know what will make you happy? Ask a stranger. Another person's objective opinion may be more informative than your own best guess. The study in Science was led by Daniel Gilbert, professor of psychology at Harvard and author of the 2007 bestseller "Stumbling on Happiness," along with Matthew Killingsworth and Rebecca Eyre, also of Harvard, and Timothy Wilson of the University of Virginia.Previous research in psychology, neuroscience, and behavioral economics has shown that people have difficulty predicting what they will like and how much they will like it, which leads them to make a wide variety of poor decisions. Interventions aimed at improving the accuracy with which people imagine future events have been generally unsuccessful.
A new study says that some aspects of peoples' cognitive skills, like making rapid comparisons, remembering unrelated information and detecting relationships, will peak at about the age of 22 and then begin a slow decline starting around age 27.Timothy Salthouse, a University of Virginia professor of psychology and the study's lead investigator, and a team conducted the study during a seven-year period, working with 2,000 healthy participants between the ages of 18 and 60.Participants were asked to solve various puzzles, remember words and details from stories, and identify patterns in an assortment of letters and symbols.
A new study says that the human brain lives "on the edge of chaos", at a critical transition point between randomness and order. Theoretical speculation? Well, yeah, but that's the nature of neuroscience.The researchers say self-organized criticality (where systems spontaneously organize themselves to operate at a critical point between order and randomness), can emerge from complex interactions in many different physical systems, including avalanches, forest fires, earthquakes, and heartbeat rhythms.
To look at Matthew Houdek, you could never tell he was born with virtually no left ear.A surgery at Loyola University Health System made it possible for Houdek to be fitted with a prosthetic ear that looks just like the real thing.Ear-nose-throat surgeon Dr. Sam Marzo implanted three small metal screws in the side of Houdek's head. Each screw is fitted with a magnet, and magnetic attraction holds the prosthetic ear in place.It takes only a few seconds for Houdek to put his prosthetic ear on in the morning and take it off when he showers or goes to bed. It doesn't fall off, and it's much more convenient than prosthetic ears that are attached with adhesive.
Humans excel at recognizing faces, but how we do this has been an abiding mystery in neuroscience and psychology. In an effort to explain our success in this area, researchers are taking a closer look at how and why we fail. A new study from MIT looks at a particularly striking instance of failure: our impaired ability to recognize faces in photographic negatives. The study, which appears in the Proceedings of the National Academy of Sciences this week, suggests that a large part of the answer might lie in the brain's reliance on a certain kind of image feature.
FINDINGS: Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.
RELEVANCE: The study reports the first time a miRNA has been shown to directly affect the p53 protein level, although researchers have previously identified other genes and miRNAs that indirectly affect p53's activity.
