Chemists at the University of Illinois have created a simple and inexpensive molecular technique that replaces an expensive atomic force microscope for studying what happens to small molecules when they are stretched or compressed. The researchers use stiff stilbene, a small, inert structure, as a molecular force probe to generate well-defined forces on various molecules, atom by atom. "By pulling on different pairs of atoms, we can explore what happens when we stretch a molecule in different ways," said chemistry professor Roman Boulatov. "That information tells us a lot about the properties of fleeting structures called transition states that govern how, and how fast, chemical transformations occur."