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African Green Monkeys And The Evolution Of HIV

African Green Monkeys And The Evolution Of HIV

Monkey viruses related to HIV may have swept across Africa more recently than previously thought, according to new research from The University of Arizona in Tucson.
A new family tree for African green monkeys shows that an HIV-like virus, simian immunodeficiency virus, or SIV, first infected those monkeys after the lineage split into four species. The new research reveals the split happened about 3 million years ago.
Previously, scientists thought SIV infected an ancestor of green monkeys before the lineage split, much longer ago.

First Atomic Bomb Test Exposed New Mexico Residents to Radiation

First Atomic Bomb Test Exposed New Mexico Residents to Radiation

On the eve of the 62nd anniversary of the world's first atomic explosion, the Trinity atomic bomb test, a CDC-led study team has reported new insights on the radiation released at the time of the test. Analyzing the doses that nearby residents received, the CDC team has made preliminary estimates of additional doses that the residents could have ingested in their bodies.
The test of a plutonium-based atomic device at the Trinity Site in southern New Mexico on July 16, 1945 was an undertaking unlike any that humankind had tried before. There was much uncertainty among the Los Alamos scientists, military personnel, and Manhattan Project officials assembled for the event as to whether the device would work and how, if it did work, it would affect the local environment.

Cost Effective Proton Therapy Device May Revolutionize Cancer Treatment

Cost Effective Proton Therapy Device May Revolutionize Cancer Treatment

Using innovative physics, researchers have proposed a system that may one day bring proton therapy, a state-of-the-art cancer treatment method currently available only at a handful of centers, to radiation treatment centers and cancer patients everywhere. Thomas R. Mackie, a professor at the University of Wisconsin and co-founder of the radiation therapy company TomoTherapy, will present this new design at next week's annual meeting of the American Association of Physicists in Medicine in Minneapolis.
Compared to the x rays conventionally used in radiation therapy, protons are potentially more effective, as they can deposit more cell-killing energy in their tumor targets and less in surrounding healthy tissue.

Eye Test Causes Severe Lethargy In Infants

Eye Test Causes Severe Lethargy In Infants

New research suggests that an eyedrop used to diagnose a rare syndrome in infants can cause severe lethargy lasting up to 10 hours and requiring hospital admission and oxygen administration.
In the article “Adverse Effects of Apraclonidine Used in the Diagnosis of Horner Syndrome in Infants”, published in the June issue of Journal of the American Association for Pediatric Ophthalmology and Strabismus, Dr. Patrick Watts and coauthors described five cases of extreme drowsiness or unresponsiveness after infants under 6 months of age were administered 1% apraclonidine eyedrops.

Designing A Better Prosthetic Arm For Military Amputees

Designing A Better Prosthetic Arm For Military Amputees

Jesse Sullivan, a double amputee from Dayton, Tenn., has been called the world's first "bionic man" with his thought-controlled, state-of-the-art prosthetic arm. He can eat with a fork, pick up a cup, paint his house or guide a weed eater by bending his advanced appendage's elbow and rotating its forearm. But he still cannot grasp and throw a baseball, cast a fishing line, tie his shoes or type on a computer keyboard as naturally as before.
That may change with the help of numerous organizations including Oak Ridge National Laboratory, some 50 miles north of Sullivan's hometown.
In 2001 while working as a utility lineman, Sullivan lost both arms after a 7000-volt shock in a power-line accident.

Gene Discovered For Type 1 Diabetes In Children

Gene Discovered For Type 1 Diabetes In Children

Pediatrics researchers at The Children’s Hospital of Philadelphia and McGill University in Montreal have identified a gene variant that raises a child’s risk for type 1 diabetes, formerly called juvenile diabetes. As investigators continue to pinpoint genes contributing to diabetes, they have their eyes on providing a scientific basis for designing better treatments and preventive measures for the disease.
The research adds a new gene and new knowledge to the four genes previously discovered for type 1 diabetes, in which the immune system destroys insulin-producing beta cells in the pancreas and makes patients dependent on frequent insulin injections to keep the body’s blood sugar under control.

The Molecular Basis Of Fear

The Molecular Basis Of Fear

Researchers from MIT have uncovered a molecular mechanism that governs the formation of fears stemming from traumatic events. The work could lead to the first drug to treat the millions of adults who suffer each year from persistent, debilitating fears - including hundreds of soldiers returning from conflict in Iraq and Afghanistan.
A study conducted by the Army in 2004 found that one in eight soldiers returning from Iraq reported symptoms of post-traumatic stress disorder (PTSD). According to the National Center for PTSD in the United States, around eight percent of the population will have PTSD symptoms at some point in their lives. Some 5.2 million adults have PTSD during a given year, the center reports.

Chlorotoxin Tumor Paint Shows Cancer Cells 500 Times Better Than MRI

Chlorotoxin Tumor Paint Shows Cancer Cells 500 Times Better Than MRI

A tumor paint developed by researchers will help surgeons see where a tumor begins and ends more precisely by illuminating the cancerous cells.
The study shows that the tumor paint can help surgeons distinguish between cancer cells and normal brain tissue in the operating room. The paint is a scorpion-derived peptide called chlorotoxin that is linked to the molecular beacon Cy5.5.Until now there has been no way to allow surgeons to see tumors “live” during surgery.

DNA Tests To Confirm Queen Hatshepsut Mummy

DNA Tests To Confirm Queen Hatshepsut Mummy

Preliminary results from DNA tests carried out on a mummy believed to be Queen Hatshepsut is expected to support the claim by Egyptian authorities that the remains are indeed those of Egypt’s most powerful female ruler.
Egyptologists in Cairo announced last month that a tooth found in a wooden box associated with Hatshepsut exactly fitted the jaw socket and broken root of the unidentified mummy.
Now, Dr Angelique Corthals, a biomedical Egyptologist at The University of Manchester, says that DNA tests she helped carry out with colleagues at the National Research Centre in Cairo have promising preliminary results suggesting the identity of the queen.

Acoustic Plasmons Could Revolutionize Data Storage

Acoustic Plasmons Could Revolutionize Data Storage

It may seem odd to think about using metallic structures for transmitting light because light quickly attenuates on passing through a metal, but light waves travelling only a few centimeters don't lose their energy and that discover could change the face of nanotechnology.
The discovery, known as acoustic plasmon, are surface plasmons formed by the group excitation of electrons but it is produced by the interaction between light and metal surfaces.
The advantage of acoustic plasmons over the long-known surface plasmons is that they are created with a different amount of energy.

What Is The Function Of All Those Proteins?

What Is The Function Of All Those Proteins?

There are hundreds of thousands of proteins for which amino acid sequence data are available, but whose structure and function remain unknown.
Now a research team, led by University of Illinois biochemistry professor John A. Gerlt, has devised a method to use a computational approach to accurately predict a protein’s function from its amino acid sequence. Their “in silico” (computer-aided) predictions were validated in the laboratory by means of enzyme assays and X-ray crystallography.
The new approach involved searching databases of known proteins for those with amino acid sequences that had the greatest homology to the unknown proteins.

Suicide Cells

Suicide Cells

When a cell is seriously stressed, say by a heart attack, stroke or cancer, a protein called Bak just may set it up for suicide, researchers have found.
In a deadly double whammy, Bak helps chop the finger-like filament shape of the cell’s powerhouse, or mitochondrion, into vulnerable little spheres. Another protein Bax then pokes countless holes in those spheres, spilling their pro-death contents into the cell.
“We found out Bak has a distinct function in regulation of the mitochondrial morphology,” says Dr. Zheng Dong, cell biologist at the Medical College of Georgia and the Veterans Affairs Medical Center in Augusta .