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Who Gets Hooked On Drugs? Rat Study Finds Genetic Markers That Influence Addiction

Who Gets Hooked On Drugs? Rat Study Finds Genetic Markers That Influence Addiction

ANN ARBOR, Mich. -- Why does one person who tries cocaine get addicted, while another might use it and then leave it alone? Why do some people who kick a drug habit manage to stay clean, while others relapse? And why do some families seem more prone to addiction than others?
The road to answering these questions may have a lot to do with specific genetic factors that vary from individual to individual, a new study in rats suggests.
Of course, an animal study can't explain all the factors that contribute to differences in addiction among humans. But the findings reveal new information about the roles played by both inherited traits and addiction-related changes in the brain.

Statins And Colorectal Cancer

Statins And Colorectal Cancer

Confounding rather than causation may explain association between statin use and lower risk of colorectal cancer

The $60 Billion Question -- Can We Prevent Norovirus?

The $60 Billion Question -- Can We Prevent Norovirus?

Each year, norovirus causes over 200,000 deaths and a global economic burden of $60 billion. A highly contagious virus that most people will contract 5 times in their lifetime, the most serious outcomes of the disease - hospitalization and death - are far more common among children and the elderly, and in low and middle income countries. In a new PLOS Collection - "The Global Burden of Norovirus & Prospects for Vaccine Development" - global norovirus experts fill critical knowledge gaps and provide key information to further development of a much-needed vaccine.
Insights from the collection

Researchers Find Brain Circuit That Controls Binge Drinking

Researchers Find Brain Circuit That Controls Binge Drinking

Researchers at the University of North Carolina at Chapel Hill have identified a circuit between two brain regions that controls alcohol binge drinking, offering a more complete picture on what drives a behavior that costs the United States more than $170 billion annually and how it can be treated.

Abnormally Low Blood Flow Indicates Damage To NFL Players' Brains

Abnormally Low Blood Flow Indicates Damage To NFL Players' Brains

The discovery of brain pathology through autopsy in former National Football League (NFL) players called chronic traumatic encephalopathy (CTE) has raised substantial concern among players, medical professionals, and the general public about the impact of repetitive head trauma. Using sophisticated neuroimaging and analytics, researchers have now identified abnormal areas of low blood flow in living professional football players. These findings, published in the Journal of Alzheimer's Disease, raises the potential for better diagnosis and treatment for persons with football related head trauma.

Citizen Scientists Collected Rare Ice Data, Confirm Warming Since Industrial Revolution

Citizen Scientists Collected Rare Ice Data, Confirm Warming Since Industrial Revolution

TORONTO, April 26, 2016 - In 1442, Shinto priests in Japan began keeping records of the freeze dates of a nearby lake, while in 1693 Finnish merchants started recording breakup dates on a local river. Together they create the oldest inland water ice records in human history and mark the first inklings of climate change, says a new report published today out of York University and the University of Wisconsin.
The researchers say the meticulous recordkeeping of these historical "citizen scientists" reveals increasing trends towards later ice-cover formation and earlier spring thaw since the start of the Industrial Revolution.

Does Learning Improve When Every Student Gets A Laptop?

Does Learning Improve When Every Student Gets A Laptop?

EAST LANSING, Mich. -- Schools that provide each student with a laptop computer, as well as the appropriate support for both students and teachers, see significant improvement in academic achievement, a new paper indicates.
Michigan State University's Binbin Zheng and colleagues analyzed years of studies on "one-to-one" laptop programs, including Zheng's own research, and found that such programs that take a comprehensive approach were linked to higher test scores in English, math, science and writing, along with other benefits.

Despite Their Small Brains -- Ravens Are Just As Clever As Chimps

Despite Their Small Brains -- Ravens Are Just As Clever As Chimps

A study led by researchers at Lund University in Sweden shows that ravens are as clever as chimpanzees, despite having much smaller brains, indicating that rather than the size of the brain, the neuronal density and the structure of the birds' brains play an important role in terms of their intelligence.
"Absolute brain size is not the whole story. We found that corvid birds performed as well as great apes, despite having much smaller brains", says Can Kabadayi, doctoral student in Cognitive Science.

Caution Advised In Over-regulating E-cigarettes As Alternative To Smoking Tobacco

Caution Advised In Over-regulating E-cigarettes As Alternative To Smoking Tobacco

Seven international tobacco control experts urged government regulators to avoid heavy-handed condemnation of e-cigarette use, in a study published online today in the journal Addiction.
The researchers noted that regulations of e-cigarettes are clearly needed, but that governments need to weigh growing evidence of the benefits e-cigarettes provide in helping some addicted cigarette smokers quit against the potential for harm if non-smokers take up vaping, the term commonly used to describe use of e-cigarettes.

Bioreactors Ready For The Big Time

Bioreactors Ready For The Big Time

URBANA, Ill. - Last summer, the Gulf of Mexico's "dead zone" spanned more than 6,400 square miles, more than three times the size it should have been, according to the Gulf Hypoxia Task Force. Nitrogen runoff from farms along the Mississippi River winds up in the Gulf, feeding algae but depriving other marine life of oxygen when the algae decomposes. The 12 states that border the Mississippi have been mandated to develop nutrient reduction strategies, but one especially effective strategy has not been adopted widely: bioreactors.

Fighting Against Counterfeit Medicine

Fighting Against Counterfeit Medicine

EAST LANSING, Mich. - Around the world, especially in developing nations, counterfeit medicines are a real problem. Until now, in many countries there hasn't been a standard protocol to conduct investigations and pursue prosecution.
New research, led by Michigan State University and featured in the current issue of the Journal of Forensic Science and Criminology, is providing the foundation to apply criminology theory to preventing the production and sale of fake and substandard medicines.

If Your Favorite Brand Is Sincere, Is Innovation What You Expect?

If Your Favorite Brand Is Sincere, Is Innovation What You Expect?

EUGENE, Ore. -- April 25, 2016 -- Open the box of that new smartphone. Oops, it feels differently from expectations based on what you'd seen. Embrace it or be disappointed? Your reaction is likely tied to your perception of the brand, says Aparna Sundar of the University of Oregon.
A brand viewed as exciting has wiggle room to introduce innovations that don't match consumers' expectations, said Sundar, a professor of marketing in the Lundquist College of Business. Not so for a brand seen as sincere, she said.