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Order Matters: Sequence Of Genetic Mutations Determines How Cancer Behaves

Order Matters: Sequence Of Genetic Mutations Determines How Cancer Behaves

The order in which genetic mutations are acquired determines how an individual cancer behaves, according to research from the University of Cambridge, published today in the New England Journal of Medicine.
Most of the genetic mutations that cause cancer result from environmental 'damage' (for example, through smoking or as a result of over-exposure to sunlight) or from spontaneous errors as cells divide. In a study published today, researchers at the Department of Haematology, the Cambridge Institute for Medical Research and the Wellcome Trust/Medical Research Council Stem Cell Institute show for the first time that the order in which such mutations occur can have an impact on disease severity and response to therapy.

Ocean Acidification You Can See From Space

Ocean Acidification You Can See From Space

Remote monitoring of large swathes of otherwise inaccessible ocean using satellites reveals an alarming picture: ocean acidity.The Earth's oceans take up about a quarter of global CO2 emissions, which can turn the seawater more acidic, making it more difficult for some marine life to live. Rising CO2 emissions, and the increasing acidity of seawater projected over the next century, has the potential to devastate some marine ecosystems, a food resource on which we rely, and so careful monitoring of changes in ocean acidity is crucial.Total ocean alkalinity as viewed from space. Credit: Ifremer/ESA/CNES

Rural China's Unsustainable Ecological Decline

Rural China's Unsustainable Ecological Decline

The agricultural development of the Lower Yangtze River Basin around Nanjing and Shanghai is ecologically unsustainable and actions are needed soon to reverse its decline, according to a new study.The region has been in environmental decline since it passed a tipping point in the late 1970s, which further found that:* the relatively stable pre-1970s 'agriculture-ecology' system in the region reached a tipping point at the end of the 1970s, as reforms in China allowed farmers to grow surplus crops with more fertilizers and pesticides.* economic development has created a 'trade-off' between gains in agricultural productivity and increasing environmental degradation, with losses of ecosystem services, such as good water quality and stable soils.

Natural Disturbances: Climate Change May Cause Loss Of Ice Dynamics In Streams

Natural Disturbances: Climate Change May Cause Loss Of Ice Dynamics In Streams

Winter floods are important natural 'disturbances' for maintaining species-rich riparian zones along northern watercourses. Movies like The Day After Tomorrow and An Inconvenient Truth exaggerated some of the big effects of a climate gone crazy but less attention is given to smaller, realistic scenarios, like a disturbance in existing winter floods.Riparian forests are important as they supply habitat, store carbon, provide shading, and filter water. Ice formation and winter floods are significant factors for vegetation and wildlife in northern regions.  According to Ph.D. candidate Lovisa Lind at Umeå universitet, during cold winter days, frazil ice (tiny ice particles) forms in the super-cooled water of open turbulent stream reaches.

Lobbying Works Behind The Scenes, But Protests Work Out Front

Lobbying Works Behind The Scenes, But Protests Work Out Front

Contrary to common belief, politicians are not in the pocket of highly-paid environmental, corporate or union lobbyists. They certainly do what lobbyists want, as long as it isn't getting too much attention, but government gets a lot more responsive when publicity is attached.

Massive Clouds Shot 100 Miles Into The Mars Atmosphere, And No One Knows Why

Massive Clouds Shot 100 Miles Into The Mars Atmosphere, And No One Knows Why

Plumes that reached over 100 miles above the surface of Mars, reported by citizen scientist astronomers in March and April 2012, continue to puzzle scientists. In the past, similar events had been seen, but only up to around 50 miles.  The features developed in less than 10 hours, covering an area of up to 1000 x 500 kilometers, and remained visible for around 10 days, changing their structure from day to day. None of the spacecraft orbiting Mars saw the features because of their viewing geometries and illumination conditions at the time but citizen scientists and their telescopes did. 

Science 2.0: Network Analysis Versus Privacy

Science 2.0: Network Analysis Versus Privacy

Protecting privacy in an age of online big data is difficult and social network data adds its own challenges, something that has been a concern since Science 2.0 began in 2006, when genomic data was really beginning its ascent. 

The Long-Term Married Are Having Sex More Often Than Ever

The Long-Term Married Are Having Sex More Often Than Ever

Youth may be idealized but that doesn't mean older people aren't getting busy - they just don't take pictures on their cell phones and post them to Instagram. A new survey found that people in the early years of marriage have sex more frequently, and sexual activity tapers off over time, but then a rebound occurs after 50 years.

Mesothelioma In Southern Nevada Likely Result Of Natural Asbestos

Mesothelioma In Southern Nevada Likely Result Of Natural Asbestos

Malignant mesothelioma has been found at higher than expected levels in women and in individuals younger than 55 years old in the southern Nevada counties of Clark and Nye, likewise in the same region carcinogenic mineral fibers including actinolite asbestos, erionite, winchite, magnesioriebeckite and richterite were discovered.
Malignant mesothelioma is a fatal cancer associated with asbestos, a set of six naturally occurring silicate minerals, exposure that develops on the outer linings of the lungs. The 3-year survival rate is only 8% and there are limited therapeutic options.

Wisdom Or Woo? Survey Shows American Rise And Fall Of Natural Products

Wisdom Or Woo? Survey Shows American Rise And Fall Of Natural Products

A nationally representative survey shows that natural product use in the United States has shifted since 2007, with some products becoming more popular and some falling out of favor. Overall, natural products (dietary supplements other than vitamins and minerals) remain the most common alternative medicine.
If you think these products rise and fall based on television and diet fads that get mainstream media attention, you would be correct.

Pollution And Suicide: Middle-aged Men At Highest Risk After Breathing Poor Air

Pollution And Suicide: Middle-aged Men At Highest Risk After Breathing Poor Air

A new study from the University of Utah is adding to the small, but growing body of research that links air pollution exposure to suicide.
In research published today in The American Journal of Epidemiology, investigator Amanda Bakian, Ph.D., an assistant professor of psychiatry at the University of Utah, and her colleagues outline chemical and meteorological variables that are risk factors for suicide. Their study, titled "Risk assessment of air pollution and suicide," examines how those factors play out among different genders and age groups. The findings build on other research by Bakian released in April 2014, when she found that fine particulates and nitrogen dioxide in air pollution are linked with an increased risk for suicide.