News Articles

Scientists have identified yet another risk from a high-salt diet. High concentrations of salt in the stomach appear to induce gene activity in the ulcer-causing bacterium Helicobacter pylori, making it more virulent and increasing the likelihood of an infected person developing a severe gastric disease.
"Apparently the stomach pathogen H. pylori closely monitors the diets of those people whom it infects. Epidemiological evidence has long implied that there is a connection between H. pylori and the composition of the human diet. This is especially true for diets rich in salt," says Hanan Gancz, of the Uniformed Services University of the Health Sciences in Bethesda, Maryland.

In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in significant improvement in the primary endpoint, the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score.
In this six-week, randomized, placebo-controlled study atypical antipsychotic aripiprazole was added to antidepressants in patients who did not have an adequate response to ADT alone. (1)(Berman, 2007, APA Poster) These findings are from one of two completed studies evaluating adjunctive aripiprazole with ADT.

A new study presented at the American Thoracic Society 2007 International Conference finds that obese people are significantly more likely to have persistent or severe persistent asthma than their thinner counterparts.
The study presented on May 23 looked at 3,059 adults with asthma, who were divided into three groups: non-overweight, overweight and obese, based on their body mass index (BMI). Compared with non-overweight asthma patients, obese patients (BMI=30) were more likely to report having continuous symptoms, have more ER visits, miss more days of work, use more rescue inhaler medications and use inhaled steroids to control asthma.

Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria.
Malaria is one of the leading causes of death in children in Africa. One of the reasons the control of malaria has been difficult is because of increasing resistance to some drugs, leading to changes in antimalarial treatment recommendations, according to background information in the article. Combination therapies have replaced monotherapies as the recommended treatments for uncomplicated malaria. However, it is not clear which treatment regimens are most effective.

Pancreatic cancer is among the deadliest of today's cancers due to limited tools for early diagnosis and few effective treatments. Research presented today takes a closer look at pancreatic cancer and the conditions that may lead to it, such as chronic pancreatitis, to evaluate the progress made to date, as well as the promising new applications of technology that will improve survival rates in the coming years. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

Scientists have made a breakthrough in understanding how cancers spread in what could lead to new ways of beating the disease.
The University of Manchester study used embryonic stem (ES) cells to investigate how some tumours are able to migrate to other parts of the body, which makes the treatment of cancer much more difficult.
Dr Chris Ward, in the University’s Faculty of Medical and Human Sciences, studied a crucial change that makes cancer cells able to start moving and spread into other tissues.
Normal cells, as well as early cancer cells, are called epithelial cells because they bind tightly to each other forming stable layers of tissue. However, as a tumour becomes more advanced, some of the cells change to become ‘mesenchymal’.

Circadian clocks regulate the timing of biological functions in almost all higher organisms. Anyone who has flown through several time zones knows the jet lag that can result when this timing is disrupted.
Now, new research by Cornell and Dartmouth researchers explains the biological mechanism behind how circadian clocks sense light through a process that transfers energy from light to chemical reactions in cells.

Colonoscopies are considered the gold standard for detecting colon cancer, the second leading cause of cancer deaths in the United States. Research presented today at Digestive Disease Week® 2007 (DDW®) discusses contributing factors that could prevent patients from getting optimal results from their colonoscopy, including age of the patient, location of the screening and proper technician training.

Scientists have refuted a longstanding theory of how HIV slowly depletes the body’s capacity to fight infection, in new research published today.
The researchers were looking at T helper cells, a class of white blood cells which recognise infection and co-ordinate the body’s immune defences. They are attacked by HIV, and their numbers gradually decline in HIV positive patients. It has long been a major puzzle why this process of depletion is so slow, often taking 10 years or more.

Wild relatives of plants such as the potato and the peanut are at risk of extinction, threatening a valuable source of genes that are necessary to boost the ability of cultivated crops to resist pests and tolerate drought, according to a new study released today by scientists of the Consultative Group on International Agricultural Research (CGIAR). The culprit is climate change, the researchers said.

It's a scenario straight out of Gray's Anatomy – a paramedic or doctor plops a mask over the face of a person struggling to breathe and begins dispensing pure oxygen.
Yet growing research suggests that inhaling straight oxygen can actually harm the brain. For the first time, a new UCLA brain-imaging study reveals why. The findings fly in the face of national guidelines for medical practice and recommend a new approach adding carbon dioxide to the gas mix to preserve brain function in patients.

Applying topical retinol to the skin appears to improve the wrinkles associated with natural aging and may help to promote the production of skin-building compounds, according to a report in the May issue of Archives of Dermatology.
The wrinkles and brown spots associated with aging appear first and most prominently on skin exposed to the sun, according to background information in the article.