Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Synovial fluid is slime with a serious purpose: Protecting shoulders, hips and other joints from wear, reducing the likelihood of injuries and arthritis.
Scientists have long believed that synovial fluid gets its surface-slicking, shock-absorbing properties from the "goo molecule" hyaluronate. But new research led by Brown University physician and engineer Gregory Jay, M.D., shows that the protein lubricin is also a player, not only lubricating cartilage but also giving synovial fluid its spring.
Livermore researchers have moved one step closer to being able to turn on and off the decay of a nuclear isomer.
The protons and neutrons in a nucleus can be arranged in many ways. The arrangement with the lowest energy is called the ground state and all others are called excited states. (This is analogous to the ground and excited states of electrons in an atom except that nuclear excited states are typically thousands of times higher in energy.) Excited nuclear states eventually decay to the ground state via gamma emission or to another nucleus via particle emission. Most excited states are short-lived (e.g., billionth of a second). However, a few are long-lived (e.g., hours) and are called isomers.
Adapting to the global climate change impacts outlined in the IPCC's Working Group 2 Report, "Climate Change 2007: Impacts, Adaptation and Vulnerability", will require new evaluation tools to help choose the best way forward, according to the International Geosphere-Biosphere Programme (IGBP), an international network of environmental scientists.
This quest for adaptation strategies opens a new chapter in global environmental change research that requires not only continued development of sophisticated climate models (and understanding the processes behind them) but also a new integration of those models with predictive descriptions of human behaviour.
A study of herbal kelp supplements led by UC Davis public health expert Marc Schenker concludes that its medicinal use may cause inadvertent arsenic poisoning and health dangers for consumers, especially when overused. Schenker and two researchers evaluated nine over-the-counter herbal kelp products and found higher than acceptable arsenic levels in eight of them.
The new study, published in the April issue of Environmental Health Perspectives (http://www.ehponline.org/) was prompted by the case of a 54-year-old woman who was seen at the UC Davis Occupational Medicine Clinic following a two-year history of worsening alopecia (hair loss), fatigue and memory loss.
If solar power is going to play a significant role in the energy equation of the future, there must be advances in technologies to store that power and more investment by manufacturers, concludes a new federally funded study by University of Massachusetts Amherst scientist Erin Baker.
The report by Baker and colleagues explores the viability of sun-fueled technologies through a combination of evaluations by experts and economic modeling, allowing the researchers to look at solar power’s role in the electricity sector in 15-year chunks through 2095.
Tai Chi, a traditional Chinese form of exercise, may help older adults avoid getting shingles by increasing immunity to varicella-zoster virus (VZV) and boosting the immune response to varicella vaccine in older adults, according to a new study published in print this week in the Journal of the American Geriatrics Society.
This National Institutes of Health (NIH)-funded study is the first rigorous clinical trial to suggest that a behavioral intervention, alone or in combination with a vaccine, can help protect older adults from VZV, which causes both chickenpox and shingles.
Premenopausal women who were assigned to follow the Atkins diet for one year lost more weight when compared to women who were assigned to follow the Zone, Ornish and LEARN diets, according to a study in the March 7 issue of JAMA.
Overweight and obesity are well-documented problems in the United States. National dietary weight loss guidelines (a diet low in calories and fat, high in carbohydrates) have been challenged, particularly by supporters of low-carbohydrate diets. However, limited evidence has been available to effectively evaluate other diets, according to background information in the article.
A new study in Journal of Personality shows that selfless and social behavior is not purely a product of environment, specifically religious environment. After studying the behavior of adult twins, researchers found that, while altruistic behavior and religiousness tended to appear together, the correlation was due to both environmental and genetic factors.
According to study author Laura Koenig, the popular idea that religious individuals are more social and giving because of the behavioral mandates set for them is incorrect. "This study shows that religiousness occurs with these behaviors also because there are genes that predispose them to it."
Henry Ford has long been heralded as the father of modern mass automotive production.
However, a controversial new paper by two Cardiff University researchers suggests that history may have got the wrong man. Dr Paul Nieuwenhuis and Dr Peter Wells of the Centre for Automotive Industry Research, Cardiff Business School, suggest it was Edward G Budd of Philadelphia whose development of the pressed steel car body truly developed mass production as it is known today.
Teens who are most physically active and consume the most calories are the leanest, researchers say.
"The take-home message would be to encourage your child to do as much vigorous physical activity as possible, including at least one hour of moderate to vigorous physical activity on a daily basis," says Dr. Paule Barbeau, exercise physiologist at the Medical College of Georgia and corresponding author on the paper in the April issue of The International Journal of Obesity. "This allows your child to eat more calories, which encourages more healthy eating habits while remaining in energy balance." Unfortunately, even the leanest of the 661 healthy black and white Augusta teens didn't have great eating habits, researchers note.
As the United States looks to alternate fuel sources, ethanol has become one of the front runners. Farmers have begun planting corn in the hopes that its potential new use for corn will be a new income source. What many don't realize, is the potential for other crops, besides corn, to provide an alternate energy source to fossil fuels. Scientists studied the greenhouse gas emissions and bioenergy of corn, hybrid poplar, switchgrass, and other crops to determine the efficiency of various biocrops in terms of energy consumption and energy output.
Astronomers using data from several X-ray satellites have caught a magnetar – the remnant of a massive star with an incredibly strong magnetic field – in a sort of giant cosmic blench.
When it comes to eerie astrophysical effects, the neutron stars commonly known as magnetars are hard to beat. The massive remnants of exploded stars, magnetars are the size of mountains but weigh as much as the sun, and have magnetic fields hundreds of trillions of times more powerful than the Earth's, which pushes our compass needles north.
The left panel shows the image of the field before the burst. The magnetar is brighter in the right panel, taken after the burst.