Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Cartilaginous fishes (sharks, rays, skates, and chimaeras) are the phylogenetically oldest group of living jawed vertebrates. They are also an important outgroup for understanding the evolution of bony vertebrates such as human and teleost fishes. In a new study published online this week in the open access journal PLoS Biology, Byrappa Venkatesh, Sydney Brenner, and colleagues performed survey sequencing (1.4× coverage) of a chimaera, the elephant shark (Callorhinchus milii).
Whose tastes do you trust more? The person who loves the same things you love? Or the person who hates the same things you hate? Turns out, when we’re looking for advice, positivity reigns. A new study reveals that we trust those who love the same things we love more than those who hate the same things we hate. As the researchers explain in the March issue of the Journal of Consumer Research, "There are few ways that products are loved, but many ways that they are hated."
A new molecular "fishing" technique developed by researchers at Duke University and Duke's Pratt School of Engineering lays the groundwork for future advances in hand-held sensing devices.
Hand-held devices used for medical testing or environmental and food-safety monitoring could quickly and precisely measure concentrations of virtually any chemical substance, including blood proteins, toxic pollutants and dangerous biological agents, in a test solution, according to the researchers.
Cultured fish cell lines and organs such as gills, heart, liver and intestines are being used to investigate the effects of toxins on fish such as freshwater trout and carp in a move to cut down the number of experiments carried out on live fish. Fish Biologists will be presenting new culture methods to help replace the use of live fish for safety testing of chemicals when they meet in Glasgow for the Annual Main Meeting of the Society for Experimental Biology on Sunday 1st April 2007.
Treatment of mice with a ‘friendly’ bacteria, normally found in the soil, altered their behavior in a way similar to that produced by antidepressant drugs, reports research published in the latest issue of Neuroscience.
These findings, identified by researchers at the University of Bristol and colleagues at University College London, aid the understanding of why an imbalance in the immune system leaves some individuals vulnerable to mood disorders like depression.
Tree frogs have the unique ability to stick to smooth surfaces even when they are tilted well beyond the vertical - some small tree frogs can even adhere when completely upside down. Conversely when walking or jumping they can detach their toe pads easily. Researchers from the University of Glasgow will present insights into how this fascinating ability is controlled at the Society for Experimental Biology’s Annual Meeting in Glasgow, UK.
“The toe pads of tree frogs are coated with a thin mucus which adhere to surfaces by wet adhesion, like wet tissue paper sticking to glass.
Inherent gender differences – instead of more sun exposure – may be one reason why men are three times more likely than women to develop certain kinds of skin cancer, say researchers at Ohio State University Medical Center.
Squamous cell carcinoma is the second most common form of skin cancer, accounting for nearly 200,000 new cases in the United States each year. While occurring more often than melanoma, squamous cell carcinoma is not nearly as worrisome. Still, it can be lethal in some patients, especially those with suppressed immune systems, including transplant recipients or people who are HIV-positive.
In the April 1 issue of Genes & Development, a Korean research team led by Dr. Kyong-Tai Kim (Pohang University) describes how melatonin production is coordinated with the body's natural sleep/wake cycles.
Something old is now something new, thanks to Lamar University researcher Jim Westgate and colleagues. The scientists' research has led to the discovery of a new genus and species of primate, one long vanished from the earth but preserved in the fossil record.
A diet high in carbohydrates but low on the glycemic index, which measures the impact of carbohydrates on blood sugar levels, may help promote weight loss, decrease body fat and reduce cardiovascular disease risk, according to a report in the July 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Carbohydrates have been at the center of recent debates about the best diet for weight loss, according to background information in the article. Public attention has focused on low–glycemic index and high-protein regimens. Clinicians continue to recommend low-fat, high-carbohydrate plans; concerned that many sources of protein are high in saturated fats, physicians and nutrition experts have called for more research into the benefits and risks of each diet.
Not from marijuana but from ... ethanol.
Many will be familiar with cravings for sweet food after having overindulged in alcohol the night before. Some may have cravings for salty foods after using marijuana - in Amsterdam, where it is legal, of course.
It appears that Egyptian fruit bats also crave particular types of sugar to reduce the effects of ethanol toxicity. Francisco Sanchez from the Ben-Gurion University of the Negev (Israel) will present data demonstrating this on Sunday 1st of April at the Society for Experimental Biology’s Annual Meeting in Glasgow.
Original photo ( not the text): Francisco Sanchez
French CNRS scientists in collaboration have shown that a memory of a traumatic event can be wiped out, although other, associated recollections remain intact. This is what a scientist in the Laboratory for the Neurobiology of Learning, Memory and Communication (CNRS/Orsay University), working with an American team, has recently demonstrated in the rat. This result could be used to cure patients suffering from post-traumatic stress.