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A sweet step toward new cancer therapies

A sweet step toward new cancer therapies

By recognizing sugars, a technique developed by University of Michigan analytical chemist Kristina Hakansson sets the stage for new cancer diagnosis and treatment options.
A growing body of evidence points to assemblies of sugars called glycans attached to proteins on cancer cell surfaces as accomplices in the growth and spread of tumors. Researchers have been keen to characterize these glycans, but traditional analytical methods have not been sufficient.

Novel experiments on cement yield concrete results

Novel experiments on cement yield concrete results

Using a brace of the most modern tools of materials research, a team from the National Institute of Standards and Technology (NIST) and Northwestern University has shed new light on one of mankind’s older construction materials—cement. Their refinements to our understanding of how cement and concrete actually work, reported this week in Nature Materials,* ultimately may make possible improvements in the formulation and use of cement that could save hundreds of millions of dollars in annual maintenance and repair costs for concrete structures and the country’s infrastructure.

The Psychology Of Baseball

The Psychology Of Baseball

It’s the seventh game of the World Series — bottom of the ninth inning, your team is down 4-3 with runners on second and third — and you’re on deck. You watch as your teammate gets the second out. That means you’re up with a chance to win a championship for your team...or lose it.
You’re known as a clutch hitter, and you’ve hit safely in 22 straight games — an impressive streak to be sure. But as you step into the batter’s box, your hands are sweating and your mind is racing. You think about the last time you faced this pitcher and the curveball he threw to strike you out. You look at him standing on the mound and he looks tired. You try to pick up clues from his body language. How fast is his fastball today? Will he tempt you with that curveball again?

Titanium dioxide -- It slices, it dices ...

Titanium dioxide -- It slices, it dices ...

Chemists from the National Institute of Standards and Technology (NIST) and Arizona State University have proposed an elegantly simple technique for cleaving proteins into convenient pieces for analysis.

Baseball Predictions The Science Way

Baseball Predictions The Science Way

The New York Mets should expect to win about 90 games in 2007 and the Yankees a whopping 110 games to lead their divisions, said Bruce Bukiet, PhD, an associate professor of mathematical sciences at New Jersey Institute of Technology (NJIT). Bukiet, who is also an associate dean of NJIT’s College of Science and Liberal Arts offers the expectations for the number of games each major league baseball team should win based on his mathematical model, developed in 2000.

Sandia researchers help to understand climate change

Sandia researchers help to understand climate change

Sandia National Laboratories researchers Mark Ivey and Bernie Zak are members of a research team from around the world whose work on the cold tundra in northern Alaska is helping to transform scientists' understanding of what the future may hold for Earth's climate.
The team conducts research at the North Slope of Alaska east of Barrow along the coast of the Chukchi Sea.

Instrument clusters near Barrow, Alaska, gather data useful in refining global climate models. (Photo by Mark Ivey)

Engineering peptides to probe proteins deep inside cell membranes

Engineering peptides to probe proteins deep inside cell membranes

Proteins, which form much of the molecular machinery required for life, are the targets of most drug molecules. One third of all proteins are membrane proteins – embedded within the cell’s fatty outer layer. While scientists can easily study the other two-thirds using such tools as antibodies, they have not had such methods to investigate the membrane-embedded portions of proteins.
To probe the secrets of these seemingly inaccessible proteins, researchers at the University of Pennsylvania School of Medicine have designed peptides that are able to bind to specific regions of transmembrane proteins, using computer algorithms, and information from existing protein sequence and structure databases.

London residents get smog alerts - by text message

London residents get smog alerts - by text message

The city of London, with funding from the European Space Agency, has launched AirTEXT, which delivers air pollution alerts and health advice via SMS text messages.
AirTEXT is a free service aimed at those who have been diagnosed with asthma, emphysema, bronchitis, heart disease or angina as well as for those who live or work in London. The service has operated in the Borough of Croydon, the largest borough by population, since July 2005 and has received a positive response with 80 percent of users saying it has helped them manage their symptoms better and reduce their exposure to air pollution.

Elementary school classrooms get low marks

Elementary school classrooms get low marks

For all the current emphasis on standardized testing and teaching requirements, the quality of elementary school instruction is mediocre at best, according to a study from the NICHD Study of Early Child Care and Youth Development study published in the March 30 issue of Science magazine.
"Any given child has less than a 20 percent chance of having a rich classroom experience consistently through elementary school," says Robert C. Pianta, lead researcher and Novartis US Foundation Professor of Education in the University of Virginia Curry School of Education. And for low-income children, the percentage is even less.

Impossible asteroid siblings

Impossible asteroid siblings

Combining precise observations obtained by ESO's Very Large Telescope with those gathered by a network of smaller telescopes, astronomers have described in unprecedented detail the double asteroid Antiope, which is shown to be a pair of rubble-pile chunks of material, of about the same size, whirling around one another in a perpetual pas de deux. The two components are egg-shaped despite their very small sizes.
The asteroid (90) Antiope was discovered in 1866 by Robert Luther from Dusseldorf, Germany. The 90th asteroid ever discovered, its name comes from Greek mythology.

MIT's ocean model precisely mimics microbes' life cycles

MIT's ocean model precisely mimics microbes' life cycles

Scientists at MIT have created an ocean model so realistic that the virtual forests of diverse microscopic plants they "sowed" have grown in population patterns that precisely mimic their real-world counterparts.
This model of the ocean is the first to reflect the vast diversity of the invisible forests living in our oceans-tiny, single-celled green plants that dominate the ocean and produce half the oxygen we breathe on Earth. And it does so in a way that is consistent with the way real-world ecosystems evolve according to the principles of natural selection.