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The Art Of Cognitive Rehabilitation Therapy

The Art Of Cognitive Rehabilitation Therapy

There is a growing need for Cognitive Rehabilitation Therapy (CRT) due to  athletes with sports-related head injuries, a growing population with age-related cognitive decline and soldiers returning from war zones with brain injuries.
A special collection of articles in NeuroRehabilitation illustrates the art and science of restoring mental functioning in those who have suffered a debilitating injury or who may otherwise have problems with attention, comprehension, learning, remembering, problem solving, reasoning, and processing.

New Technique Could Be Used To Search Space Dust For Life's Ingredients

New Technique Could Be Used To Search Space Dust For Life's Ingredients

While the origin of life remains mysterious, scientists are finding more and more evidence that material created in space and delivered to Earth by comet and meteor impacts could have given a boost to the start of life. Some meteorites supply molecules that can be used as building blocks to make certain kinds of larger molecules that are critical for life.

Simple, At-home Test Will Detect Most Colorectal Cancers

Simple, At-home Test Will Detect Most Colorectal Cancers

February 03, 2014, OAKLAND, Calif. —Tests that require patients to collect a single stool sample at home and then send it to a lab for analysis will detect about 79 percent of colorectal cancers, according to a new evidence review published in the Annals of Internal Medicine. The review of 19 studies examining eight different fecal immunochemical tests, know as "FITs", also finds that the tests will correctly identify about 94 percent of patients who do not have cancers of the rectum or colon.
"We know the FIT is easy to use, and now we also know that it is a great tool for assessing which patients have cancer and which patients don't," said Beth Liles, MD, review co-author and clinical investigator at the Kaiser Permanente Center for Health Research in Portland, Ore.

Scientists Call For Screening Mammography Every 2 Years For Most Women

Scientists Call For Screening Mammography Every 2 Years For Most Women

Adoption of new guidelines recommending screening mammography every two years for women ages 50 to 74 would result in breast cancer screening that is equally effective, while saving the United States $4.3 billion a year in health care costs, according to a study led by UC San Francisco.
The study compares three possible mammography screening strategies with a model of current U.S. screening practices.
The article appears on February 4, 2014 in Annals of Internal Medicine.

Marker May Predict Response To Ipilimumab In Advanced Melanoma

Marker May Predict Response To Ipilimumab In Advanced Melanoma

PHILADELPHIA — Among patients with advanced melanoma, presence of higher levels of the protein vascular endothelial growth factor (VEGF) in blood was associated with poor response to treatment with the immunotherapy ipilimumab, according to a study published in Cancer Immunology Research, a journal of the American Association for Cancer Research.
The study suggests combining immunotherapy with VEGF inhibitors, also known as angiogenesis inhibitors, may be a potential option for these patients.

How Fat Might Be Controlled Through The Body Clock

How Fat Might Be Controlled Through The Body Clock

Australian researchers have shed more light on an underexplored aspect of the important brain-signaling system that controls appetite, body composition and energy use. Their findings suggest that a specific gene regulating our body clock may play a central role in determining how fat we become.
Evolution has preserved the 'neuropeptide Y (NPY) system', as it is known, in most species – indicating its importance – and much of our understanding comes from studying it in mice. There is one important difference, however, between the NPY system in mouse and man.
In man, the neurotransmitter NPY communicates with four well-known 'cell surface receptors' in the brain (Y1, Y2, Y4 and Y5), which in turn trigger the system's effects.

Some Brain Regions Retain Enhanced Ability To Make New Connections

Some Brain Regions Retain Enhanced Ability To Make New Connections

In adults, some brain regions retain a "childlike" ability to establish new connections, potentially contributing to our ability to learn new skills and form new memories as we age, according to new research from Washington University School of Medicine in St. Louis and the Allen Institute for Brain Science in Seattle.
The scientists arrived at the new findings by comparing gene activity levels in different regions of the brain. They identified adult brain regions where genes linked to the construction of new connections between cells have higher activity levels. The same genes are also highly active in young brains, so the researchers called this pattern of gene activity childlike.

Is Multitasking Mastery In The Genes?

Is Multitasking Mastery In The Genes?

Human factors/ergonomics researchers have long studied the connection between cognitive function and the ability to perform well on multiple simultaneous tasks, and recently a group of neuroergonomics researchers went a step further to examine a genetic link to multitasking ability. Neuroergonomics is the study of the brain in relation to performance.

Microbe Community Changes May Reduce Amazon's Ability To Lock Up Carbon Dioxide

Microbe Community Changes May Reduce Amazon's Ability To Lock Up Carbon Dioxide

UT Arlington researchers focusing on the Amazon recently found that widespread conversion from rainforest to pastureland has significant effects on microorganism communities that may lead to a reduction in the region's role as a reservoir for greenhouse gas.
The Amazon rainforest is the largest terrestrial reservoir or "sink" for carbon dioxide, a gas that has been linked to climate change. Through photosynthesis, the Amazon absorbs 1.5 billion tons of carbon dioxide from the atmosphere every year in a process that requires input of nitrogen.

The Epigenetics Of Breast Cancer Family History

The Epigenetics Of Breast Cancer Family History

Breast cancer runs in families; however, genetic predisposition (such as being BRCA1 or BRCA2 mutation carriers) explains only a portion of this observation. Epigenetic changes (modifications in the genome that alter gene expression but do not affect the DNA sequence per se) have been shown to also play a role in breast cancer risk.

Ramularia And The 4 Rs

Ramularia And The 4 Rs

The gene that has provided spring barley with resistance to powdery mildew for over 30 years increases susceptibility to newly-important disease Ramularia leaf spot.
Scientists confirm the trade-off in a paper published in the Journal of Experimental Botany. Since 1980, the mlo gene has transformed mildew from the most important disease of barley to an occasional nuisance in wetter areas of the UK.
"Having suspected that one of the most successful and widely-used resistances to an important crop disease has the detrimental effect of increasing susceptibility to another, we took a closer look," says Professor James Brown from the John Innes Centre.