Hot vents on the seabed could have spontaneously produced the organic molecules necessary for life, according to a model which shows how the surfaces of mineral particles inside hydrothermal vents have similar chemical properties to enzymes, the biological molecules that govern chemical reactions in living organisms.

This means that vents are able to create simple carbon-based molecules, such as methanol and formic acid, out of the dissolved CO2 in the water. This would explain how some of the key building blocks for organic chemistry were already being formed in nature before life emerged - and may have played a role in the emergence of the first life forms.

As a modern bonus, it should how plastics and fuels could be synthesized from CO2 rather than oil.

The team combined laboratory experiments with supercomputer simulations to investigate the conditions under which the mineral particles would catalyze the conversion of CO2 into organic molecules. The experiments replicated the conditions present in deep sea vents, where hot and slightly alkaline water rich in dissolved CO2 passes over the mineral greigite (Fe3S4), located on the inside surfaces of the vents. These experiments hinted at the chemical processes that were underway. The simulations provided a molecule-by-molecule view of how the CO2 and greigite interacted, helping to make sense of what was being observed in the experiments. The computing power and programming expertise to accurately simulate the behaviur of individual molecules in this way has only become available in the past decade.

"We found that the surfaces and crystal structures inside these vents act as catalysts, encouraging chemical changes in the material that settles on them," says Nathan Hollingsworth, a co-author of the study. "They behave much like enzymes do in living organisms, breaking down the bonds between carbon and oxygen atoms. This lets them combine with water to produce formic acid, acetic acid, methanol and pyruvic acid. Once you have simple carbon-based chemicals such as these, it opens the door to more complex carbon-based chemistry."

Theories about the emergence of life suggest that increasingly complex carbon-based chemistry led to self-replicating molecules - and, eventually, the appearance of the first cellular life forms. This research shows how one of the first steps in this journey may have occurred. It is proof that simple organic molecules can be synthesized in nature without living organisms being present. It also confirms that hydrothermal vents are a plausible location for at least part of this process to have occurred.

 Published in Chemical Communications