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'Self-Seeding' Plays Crucial Role In Cancer Progression

'Self-Seeding' Plays Crucial Role In Cancer Progression

Cancer is commonly thought to progress by the growth of a primary tumor followed by metastasis, in which cancer cells leave the primary tumor and spread to distant organs. New research conducted by scientists at Memorial Sloan-Kettering Cancer Center shows, however, that circulating tumor cells can also return to and grow in their tumor of origin, a newly discovered process called 'self-seeding.'The findings of the study, published in the December 25 issue of the journal Cell, suggest that self-seeding can enhance tumor growth through the release of signals that promote angiogenesis, invasion, and metastasis.

Cockroach Serves As Blueprint For Running Robot

Cockroach Serves As Blueprint For Running Robot

Engineers from Oregon State University are attempting to develop a robot capable of running effortlessly over rough terrain and they're doing it with assistance from the unlikeliest of creatures--cockroaches. While they maybe unsightly, the insects are also biological and engineering marvels, and are providing the researchers  with what they call "bioinspiration" in their efforts to build a running robot.Their latest findings – just published in the professional journal Bioinspiration and Biomimetics – outline how animals use their legs to manage energy storage and expenditure, and why this is so important for running stability.

Molar Emergence Says Much About Evolution Of Apes, Humans

Molar Emergence Says Much About Evolution Of Apes, Humans

From the smallest South American monkeys to the largest African apes, the timing of molar development and eruption is closely attuned to many fundamental aspects of a primate's biology, according to Gary Schwartz, a researcher at the Institute of Human Origins and an associate professor in the School of Human Evolution and Social Change in ASU's College of Liberal Arts and Sciences.

Can Nature Adapt To Climate Change In Time?

Can Nature Adapt To Climate Change In Time?

The climate is changing and the natural world has to adapt to it. But how much time do the multitudes of species and their habitats have before it's too late? A team of environmental researchers has set out to answer that very question, and they say that as the world warms through the 21st century, ecosystems will need to shift about 0.42 kilometers per year (about a quarter mile per year) to keep pace with changing temperatures across the globe.

Duck Sex Is Even More Screwed Up Than Human Sex

Duck Sex Is Even More Screwed Up Than Human Sex

Female ducks can thank evolution for avoiding becoming impregnated by undesirable but aggressive males endowed with large corkscrew-shaped penises: vaginas with clockwise spirals that thwart oppositely spiraled males.  That's right, males are literally screwed.The research on this evolutionary 'battle of the sexes'  at the genitalia level were described in the December 23 issue of the journal Proceedings of the Royal Society B.

Vampirism And Cosmic Facelifts In Messier 30

Vampirism And Cosmic Facelifts In Messier 30

Stars in globular clusters tend to be 12-13 billion years old but a small fraction appear to be significantly younger than the average population.   Left behind by the stars that followed the normal path of stellar evolution and became red giants, those younger ones have been dubbed blue stragglers.Oddly, blue stragglers appear to regress from 'old age' back to a hotter and brighter 'youth', gaining a new lease on life in the process - a cosmic facelift.

Scientists Face-Off Over Global Warming

Scientists Face-Off Over Global Warming

Global warming may be a reality, but the debate over what causes the warming and what to do about it is nowhere near over, according to a story in the latest issue of Chemical&Engineering News (C&EN) that surveyed climate scientists on both sides of the argument.While both global warming "believers" and "skeptics" agree on some basics of climate change, for example, that average global temperatures have risen since 1850, with most of the warming occurring since the 1970s, the cordial agreement stops there, writes author Stephen K. Ritter. "At the heart of the global warming debate is whether warming is directly the result of increasing anthropogenic CO2 levels, or if it is simply part of Earth's natural climatic variation."

Rifampin - The Antibiotic That Tuberculosis Thrives On

Rifampin - The Antibiotic That Tuberculosis Thrives On

Scientists have identified a strain of antibiotic-resistant tuberculosis that thrives in the presence of rifampin, a front-line drug in the treatment of tuberculosis. The bacterium was identified in a Chinese patient, and the researchers say his condition grew worse with treatment regimens containing rifampin, before being cured with rifampin-free regimens.Their study, which will appear in the January 2010 issue of the International Journal of Tuberculosis and Lung Disease, is among the first to document the treatment of a patient with rifampin-dependent infection.

Century-Old 'M.' Uintensis Fossil  Reworks Carnivore Evolution

Century-Old 'M.' Uintensis Fossil Reworks Carnivore Evolution

More than a hundred years after its discovery, the limbs and vertebrae of a fossil have been pulled off the shelf at the American Museum of Natural History to revise the view of early carnivore lifestyles. Carnivores—currently a diverse group of mostly meat-eating mammals like bears, cats, raccoons, seals, and hyenas—had been considered arboreal in their early evolutionary history. But now that the skeleton of 'Miacis' uintensis has been unpacked from its matrix of sandstone, it is clear that some early carnivores were built to walk on the ground at least part of the time. The new research is published this month in the Journal of Vertebrate Paleontology

How Smallpox Defeats Our Immune Systems

How Smallpox Defeats Our Immune Systems

 Researchers working in a high containment laboratory at the CDC in Atlanta, GA have discovered how the smallpox virus kills. In a study published in the FASEB Journal, the team says that the virus, now eradicated by vaccination, cripples the immune systems by attacking molecules made by our bodies to block viral replication.  In a high containment laboratory at the Centers for Disease Control and Prevention in Atlanta, scientists produced the recombinant proteins from the variola virus and a similar virus that affects monkeys, causing monkeypox.  The researchers then showed that cells infected

Teens Willing To Get Violent To Fit In

Teens Willing To Get Violent To Fit In

Young people who want to be better appreciated and respected within their group are willing to be violent, says a new study that looked in depth at the social relationships between male and female teenagers, relational violence, and psycho-social adjustment factors such as loneliness and self-esteem.Published recently in Psicothema,  the study focused on the relationship between relational violence between teenagers, their social adjustment and their reputation, in order to show how young people who long for high "reputation status" are more likely to use relational violence as a tool for achieving this objective.

Music Turns Kids Into Potheads?

Music Turns Kids Into Potheads?

 Teens who frequently listen to music filled with references to marijuana are more likely to use the drug than their counterparts with less exposure to such lyrics, according to a University of Pittsburgh School of Medicine study published online in the journal Addiction. "Based on an analysis of survey data from 959 ninth-graders, we found that students who listen to music with the most references to marijuana are almost twice as likely to have used the drug than their peers whose musical tastes favor songs less focused on substance use, even after controlling for confounding factors," said Brian Primack, M.D.,Ed.M., M.S., lead author of the study and assistant professor of medicine and pediatrics at Pitt's School of Medicine.