Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
A new report published in the January 8 issue of Cell explains how plants, which are incredibly temperature sensitive, not only 'feel' the temperature rise, but also coordinate an appropriate response -- activating hundreds of genes and deactivating others; it turns out it's all about the way that their DNA is packaged. The findings may help to explain how plants will respond in the face of climate change and offer scientists new leads in the quest to create crop plants better able to withstand high temperature stress, the researchers say.
Reporting in the current online edition of the journal BMC Medicine, researchers from UCLA say they can predict the number of H1N1 flu infections that could occur during a commercial flight using novel mathematical modeling techniques. They found that transmission could be rather significant, particularly during long flights, if the infected individual travels in economy class. Specifically, two to five infections could occur during a five-hour flight, five to 10 during an 11-hour flight, and seven to 17 during a 17-hour flight.
The U.S. government's biofuels policy needs a makeover, according to researchers from Rice University. In a new study published by the university's Baker Institute for Public Policy, the team says that the economic, environmental and logistical basis for the billions of dollars in federal subsidies and protectionist tariffs that go to domestic ethanol producers every year is seriously flawed and urge lawmakers to fundamentally rethink the policy of promoting ethanol to diversify America's energy sources.
Despite astronomers hopes, the rocky planet CoRoT-7 b that was discovered circling a star some 480 light years from Earth last October is likely a forbidding place that doesn't harbor life. Upon its discovery, experts said that was because the planet is so close to its star thattemperatures might be above 4,000 degrees F (2,200 C) on the surface lit by its star and as low as minus 350 F (minus 210 C) on its dark side.
Though it seems entirely obvious at this point, eating less and exercising more are the only reliable ways to lose weight. The reason for repeating this advice ad nauseum? An international team of researchers says it's because a body of scientific literature has arisen in recent years suggesting that fat oxidation – burning the fats we eat as opposed to the carbohydrates – is enough to promote fat loss. It isn't.In a new paper published in Cell Metabolism, scientists say they have demonstrated that mice genetically altered to burn fats in preference to carbohydrates, will convert the unburned carbohydrates into stored fat anyway, and their ultimate weight and body composition will be the same as normal mice.
University of Utah biologists have found that finches – the birds Charles Darwin famously studied – develop antibodies against two parasites (a pox virus and a nest fly) that moved to the Galapagos, suggesting the birds can fight the alien invaders. With the discovery that the medium ground finches produce antibodies aimed specifically at the parasites "the next step is to determine if this immune response is helping the birds or hurting the birds," says University of Utah biology Professor Dale Clayton, who led the new study published online Wednesday, Jan 6. in PLoS ONE.
Did you have a pushy physical education teacher that made you loathe exercising at school? If so, you're not alone. New research suggets that many people may have been persuaded to permanently avoid exercise as a result of the humiliation they experienced in physical education class. In a study published in Qualitative Research in Sport and Exercise, Billy Strean, a professor in the U of A's Faculty of Physical Education and Recreation, says a negative lifelong attitude towards physical activity can be determined by either a good or a bad experience, based on the personal characteristics of the coach or instructor. For example, negative experiences may come from a teacher who has low energy, is unfair and/or someone who embarrasses students.
Researchers from the University of Florida and Oklahoma State University have found common denominators in the calls of hundreds of species of insects, birds, fish, frogs, lizards and mammals that can be predicted with simple mathematical models. Compiling data from nearly 500 species, scientists say the calls of a whole host of creatures are ultimately controlled by their uptake and use of energy, or their metabolic rates.The finding, reported in today's Proceedings of the Royal Society B, will help scientists understand how acoustic communication evolved across species, uniting a field of study that has long focused on the calls of particular groups of animals, such as birds.
Staying in a multi-bed hospital room dramatically increases the risk of acquiring a serious infectious disease, according to the findings of a study published on-line in the American Journal of Infection Control. The authors say the chance of acquiring serious infections like C. difficile (Clostridium difficile) rises with the addition of every hospital roommate. "If you're in a two, three or four-bedded room, each time you get a new roommate your risk of acquiring these serious infections increases by 10 per cent," says Dr. Zoutman, professor of Community Health and Epidemiology at Queen's. "That's a substantial risk, particularly forlonger hospital stays when you can expect to have many different roommates."
As smoking continues to decline among the US population, the rate of obesity is growing and has now become an equal, if not greater, contributor to the burden of disease and shortening of healthy life compared to smoking, according to Researchers from Columbia and The City College of New York. They say that the Quality-Adjusted Life Years (QALYs) lost due to obesity is now equal to, if not greater than, those lost due to smoking, both modifiable risk factors. The results appear in February 2010 issue of the American Journal of Preventive Medicine.
Fruits that contain anti-aromatase phytochemicals, such as pomegranates, may reduce the incidence of hormone-dependent breast cancer, according to research published in the January issue of Cancer Prevention Research. The authors say that pomegranate is enriched in a series of compounds known as ellagitannins that appear to be responsible for the fruit's anti-proliferative effect."Phytochemicals suppress estrogen production that prevents the proliferation of breast cancer cells and the growth of estrogen-responsive tumors," said principal investigator Shiuan Chen, Ph.D., director of the Division of Tumor Cell Biology and co-leader of the Breast Cancer Research Program at City of Hope in Duarte, Calif.
Shown in an extremely broad range of color and showcasing more than twelve billion years of cosmic history, Hubble's recent image is a full-glory cosmic renaissance of the history of the Universe. This image provides a record of the Universe's most exciting formative years, from the birth of stars in the early Universe all the way through the materialization of the Milky Way.