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'DNA Signature' Found In Human Sperm

'DNA Signature' Found In Human Sperm

Scientists say they have discovered a unique 'DNA signature' in human sperm, which may act as a key that unlocks an egg's fertility and triggers new life. Drs David Miller and David Iles from the University of Leeds, in collaboration with Dr Martin Brinkworth at the University of Bradford, say they have found that sperm writes a DNA signature that can only be recognized by an egg from the same species. This enables fertilization and may even explain how a species develops its own unique genetic identity. Without the right 'key', successful fertilization either cannot occur, or if it does, development will not proceed normally. Notably, disturbances in human sperm DNA packaging are known to cause male infertility and pregnancy failures. 

Antibody Drugs And Pediatric Ophthalmology  - Benefits Versus Side Effects

Antibody Drugs And Pediatric Ophthalmology - Benefits Versus Side Effects

A new class of antibody drugs may help in treatment of childhood eye diseases but specialists need to be alert for the possibility of serious side effects, according to an editorial in the August Journal of American Association for Pediatric Ophthalmology and Strabismus (AAPOS).In the editorial, Dr. Robert L. Avery discusses issues related to the use of antibodies against vascular endothelial growth factor (VEGF) in pediatric ophthalmology.

Common Sense And Science - If You Have HIV, Don't Chew Your Baby's Food

Common Sense And Science - If You Have HIV, Don't Chew Your Baby's Food

Don't chew someone else's food if you have HIV or AIDS?   Sure, that sounds like common sense but lots of things that seem like common sense to some are abstract to others - try explaining geodesics, Euclidean geometry and spacetime to people who just need a gas station and want to know the quickest route.But science does studies so common sense can be science rather than urban myth so researchers have verified cases in which HIV was almost certainly transmitted from mothers to children through pre-chewed food.

Which Foods Can Help You See Better?

Which Foods Can Help You See Better?

Your mother, despite lacking an expensive lab studying phytochemicals or a PhD (well, for most of us anyway) told you that carrots would help you see better.    And she was right, but purple carrots here and there may be even better for you because they have anthocyanins.But carrots are not the only way to go, it turns out.   New research suggests that a diet high in omega-3 fatty acids may help prevent one of the leading causes of legal blindness among the elderly.

Regaining sight from bone marrow stem cells in old age

Regaining sight from bone marrow stem cells in old age

Often the topic of controversy, stem cells research has once again proved itself necessary. University of Florida researchers were able to program bone marrow stem cells to repair damaged retinas in mice. The success in repairing a damaged layer of retinal cells in mice implies that blood stem cells taken from bone marrow can be programmed to restore a variety of cells and tissues, including ones involved in cardiovascular disorders such as atherosclerosis and coronary artery disease.

The protein structure that could prevent cataracts

The protein structure that could prevent cataracts

The human eye lens consists of a highly concentrated mix of several proteins. Protective proteins keep them from aggregating and clumping. If this protection fails, the lens blurs and the patient develops cataracts. Two research groups at the Department of Chemistry of the Technische Universitaet Muenchen (TUM) have succeeded in explaining the molecular architecture of this kind of protective protein. Their findings, which are published in PNAS (Proceedings of the National Academy of Sciences).

Why humans do and zebrafish don't get the amphetamines buzz

Why humans do and zebrafish don't get the amphetamines buzz

The effects of amphetamines on gene expression in zebrafish have been discovered. This new study, published in BioMed Central's open access journal Genome Biology, provides clues to the genetics that underlie susceptibility to addiction by describing the nad zebrafish mutant, which does not feel the rewarding effects of the drugs.

A little "spray paint" goes along way toward insulating circuits

A little "spray paint" goes along way toward insulating circuits

Ever since graphene was discovered in 2004, this one-atom thick, super strong, carbon-based electrical conductor has been billed as a "wonder material" that some physicists think could one day replace silicon in computer chips.But graphene, which consists of carbon atoms arranged in a honeycomb lattice, has a major drawback when it comes to applications in electronics: it conducts electricity almost too well, making it hard to create graphene-based transistors that are suitable for integrated circuits. In Physics World, Kostya Novoselov--a condensed-matter physicist from Manchester University--explains how their discovery of graphane, an insulating equivalent of graphene, may prove more versatile.

Protein Phosphorylation Could Be The Key To Understanding Stem Cell Differentiation

Protein Phosphorylation Could Be The Key To Understanding Stem Cell Differentiation

Stem cell researchers trying to understand the mechanisms that determine whether stem cells divide or differentiate, and what types of cells they become and how to control them to develop new treatments, may have gotten some much needed help. Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made a comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives. The study was published in the journal Cell Stem Cell.

Water In Comets - A Cometary Panspermia Origin Of Life Hypothesis

Water In Comets - A Cometary Panspermia Origin Of Life Hypothesis

Comets contained vast oceans of liquid water in their interiors during the first million years of their formation, argue Professor Chandra Wickramasinghe and colleagues at the Cardiff Centre for Astrobiology in a paper published in the International Journal of Astrobiology. The watery environment of early comets, together with the vast quantity of organics already discovered in comets, would have provided ideal conditions for primitive bacteria to grow and multiply, they say. 

Getting electrons to "jump" forces them to split apart

Getting electrons to "jump" forces them to split apart

Previously thought to be indivisible, with negative charge for all, the electron is one of the fundamental building blocks of nature. A new experiment, however, has shown that electrons, if crowded into narrow wires, are seen to split apart. The electron is responsible for carrying electricity in wires and for making magnets. These two properties of magnetism and electric charge are carried by electrons which seem to have no size or shape and are impossible to break apart.