News Articles

Women who have used Fosamax are nearly twice as likely to develop the most common kind of chronically irregular heartbeat (atrial fibrillation) than are those who have never used it, according to research from Group Health and the University of Washington published in the April 28 Archives of Internal Medicine.
Merck markets Fosamax, the most widely used drug treatment for the bone-thinning disease osteoporosis, explained study leader Susan Heckbert, MD, PhD, MPH, a professor of epidemiology and scientific investigator in the Cardiovascular Health Research Unit at the University of Washington. The Food and Drug Administration (FDA) approved the first generic versions (called alendronate) in February.

A widely used class of diabetes medications appears to be associated with an increased risk for fractures, according to a report in the April 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
“The insulin-sensitizing thiazolidinediones are a relatively new and effective class of oral antidiabetic agents that have gained wide use in clinical conditions characterized by insulin resistance,” the authors write as background information in the article. Two drugs in this category, pioglitazone and rosiglitazone, account for 21 percent of oral diabetes medications prescribed in the United States and 5 percent of those in Europe. Recent studies have suggested that these therapies may have unfavorable effects on bone, resulting in slower bone formation and faster bone loss.

Young women who took the commonly used epilepsy drug phenytoin for one year showed significant bone loss compared to women taking other epilepsy drugs, according to a study published in the April 29, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers tested the bone health of 93 women with epilepsy who were between the ages of 18 and 40 and were taking the epilepsy drugs phenytoin, carbamazepine, lamotrigine or valproate. Bone mineral density was measured at the spine and two areas of the hip, (the femoral neck and total hip) at the beginning of the study and one year later. Researchers also evaluated each woman’s nutrition and physical activity, along with other factors that affect bone health.

New heart research published inNature Genetics reveals how a gene called osteoglycin (Ogn), which had not previously been linked with heart function, plays a key role in regulating heart growth. The study suggests that the gene can behave abnormally in some people, and that this can lead to the heart becoming abnormally enlarged.
The researchers hope that through understanding how enlarged hearts are linked to the workings of genes like Ogn, they will be able to develop new treatments for the condition, which affects a large proportion of those with high blood pressure, obesity and diabetes.
Scientists believe that enlarged hearts are caused by a combination of genetic factors and external stimuli such as high blood pressure and obesity. However, the role played by genes has remained largely unknown.

Are climate change and carbon emissions inextricably linked? New research published in Carbon Balance and Management suggests that this may not be the case, although it may be some time before we reach this saturation point.
The land and the oceans contain significantly more carbon than the atmosphere, and exchange carbon dioxide with the atmosphere. The amount of CO2 emissions absorbed by the land or the oceans vary in response to changes in climate (including natural variations such as El Nino or volcanic eruptions). So current theories suggest that climate change will have a feedback effect on the rate that atmospheric CO2 increases; rising CO2 levels in turn add to global warming.
The link between the carbon cycle, and human effects caused by emissions, energy use and agriculture, may only be relevant for the next 'several centuries,’ suggest Igor Mokhov and Alexey Eliseev from the A.M. Obukhov Institute of Atmospheric Physics RAS, in Moscow, Russia. The authors used a climate model known as IAP RAS CM to study how feedback between our climate and the carbon cycle changes over time. In their simulations, the authors assumed that fossil fuel emissions would grow exponentially with a characteristic timescale from 50 to 250years.

Nitric oxide has emerged as an important signaling molecule in plants - as in mammals including people. In studies of a tropical medicinal herb as a model plant, researchers have found that nitric oxide targets a number of proteins and enzymes in plants.
In collaborative work with the research group of Renu Deswal, a faculty member, and her doctoral student at the Botany Department, University of Delhi, India, Agricultural Research Service (ARS) scientist Autar Mattoo has identified 19 such targeted proteins and enzymes in Kalanchoe pinnata, also known as "miracle leaf."
These proteins and enzymes are involved in regulating processes from seed germination to cell development to plant death.

Depending on which variant of the gene CYP1A2 a woman has, a coffee consumption rate of at least two cups a day can either reduce the total risk of developing breast cancer or delay the onset of cancer, according to new research from Lund University and Malmö University in Sweden.
The effect of coffee is related to estrogens - female sex hormones. Certain metabolic products of these hormones are known to be carcinogenic and various components of coffee can alter the metabolism so that a woman acquires a better configuration of various estrogens.
Coffee, of course, contains caffeine, which also hampers the growth of cancer cells.

'Functional foods' are those that provide a health benefit beyond basic nutrition and more people are recognizing that they are an important part of a lifestyle that leads to long-term fitness and even longevity.
Liz Sloan, writing in Food Technology, has identified the top 10 trends in functional foods. The article noted that a majority of Americans, 69 percent, are incorporating foods into a preventative lifestyle, while 27 percent are utilizing food as a treatment to manage a preexisting health condition. One-third of shoppers (36 percent) are trying to reduce the risk of developing a health condition, follow a doctor’s advice (30 percent) or manage/treat a specific condition on their own (25 percent), according to the Food Marketing Institute¹ data.
“Today’s consumers are extremely sophisticated, and they are attracted to functional foods’ ability to help manage health and wellness,” said Institute of Food Technologists(IFT) spokesperson Roger Clemens, PhD. Simply put, Americans are relying heavily on the foods they consume to improve their well-being.
Top 10 Food Trends

At Abercrombie & Fitch, little girls were sold thong underwear tagged with the phrases "eye candy" and "wink wink." In Britain, preschoolers could learn to strip with their very own Peekaboo Pole-Dancing Kits, complete with kiddie garter belts and play money. And 'tween readers of the magazine Seventeen discovered "405 ways to look hot" like Paris Hilton.
This kind of sexualization of 'tween girls - defined as those between the ages of 8 and 12 - in pop culture and advertising is a growing problem fueled by marketers' efforts to create cradle-to-grave consumers, a University of Iowa journalism professor argues in her new book.
"A lot of very sexual products are being marketed to very young kids," said Gigi Durham, author of The Lolita Effect. "I'm criticizing the unhealthy and damaging representations of girls' sexuality, and how the media present girls' sexuality in a way that's tied to their profit motives. The body ideals presented in the media are virtually impossible to attain, but girls don't always realize that, and they'll buy an awful lot of products to try to achieve those bodies. There's endless consumerism built around that."

Are you exhausted? Do you have pain all over but can’t figure out what’s wrong? If so, you may be suffering from fibromyalgia, a chronic condition that causes exhaustion, sleep disturbances and diffuse pain in your muscles, tendons, and ligaments.
Fibromyalgia patients experience a range of symptoms of varying intensities that increase and decrease over time and often resemble other conditions. For years, because of their complex nature and a lack of research on the condition, many doctors misdiagnosed fibromyalgia symptoms or dismissed them as being in the patient’s head. Even today, it is estimated to take an average of five years for a fibromyalgia patient to get an accurate diagnosis.
There is no laboratory test available to diagnose fibromyalgia. Doctors must rely on patient histories, self-reported symptoms, a physical examination and an accurate manual tender point examination.

An international team of scientists has detected that some of the glow of Earth’s aurora is polarized, an unexpected state for such emissions. Measurements of this newfound polarization in the Northern Lights may provide scientists with fresh insights into the composition of Earth’s upper atmosphere, the configuration of its magnetic field, and the energies of particles from the Sun, the researchers say.
If observed on other planets, the phenomenon might also give clues to the shape of the Sun’s magnetic field as it curls around other bodies in the solar system.
When a beam of light is polarized, its electromagnetic waves share a common orientation, say, aligned vertically, or at some other angle. Until now, scientists thought that light from energized atoms and molecules in planetary upper atmospheres could not be polarized. The reason is simple: in spite of the low number of particles at the altitudes concerned (above 100 kilometers (60 miles)), there are still numerous collisions between molecules and gas atoms. Those collisions depolarize the emitted light.

MILAN, April 26 /PRNewswire/ --
At today's sessions of the 43rd Annual Meeting of the European Association for the Study of the Liver (EASL), experts reported advances in basic research that have important implications for the eventual treatment of people with chronic liver diseases.