News Articles

A team has examined over 300,000 genetic markers in thousands of asthmatic children and compared their data with those of healthy controls. The newly found gene, ORMDL3, is a promising object of research: it could help to improve the prevention and diagnosis of asthma, and possibly to develop a new therapy.
The scientists used the fact that the genetic material of different individuals shows differences. One type of DNA variants is called SNPs, short for “Single Nucleotide Polymorphisms”. They can be compared and statistically analysed.

By creating "Teflon" versions of natural antibiotics found in frog skin, a research team led by biological chemist E. Neil Marsh has made the potential drugs better at thwarting bacterial defenses, an improvement that could enhance their effectiveness.
Marsh and collaborators work with compounds called antimicrobial peptides (AMPs), which are produced by virtually all animals, from insects to frogs to humans. AMPs are the immune system's early line of defense, battling microbes at the first places they try to penetrate: skin, mucous membranes and other surfaces. They're copiously produced in injured or infected frog skin, for instance, and the linings of the human respiratory and gastrointestinal tracts also crank out the short proteins in response to invading pathogens.

Non-medicinal interventions are highly effective in preventing the behavioral and academic problems associated with Attention Deficit Hyperactivity Disorder (ADHD), according to a five-year study led by researchers at Lehigh University’s College of Education.
The study, titled “Project Achieve” and funded by the National Institute of Mental Health (NIMH), was the largest of its kind focusing on children aged 3 to 5 who have shown significant symptoms of ADHD. It also involved researchers from Lehigh Valley Hospital in Allentown, Pa.
The researchers, led by George DuPaul, professor of school psychology at Lehigh; Lee Kern, professor of special education at Lehigh; and Dr.

Researchers at Pacific Northwest National Laboratory are uniting theory, computation and experiment to discover exactly how heavy elements, such as uranium and technetium, interact in their environment.
As part of that effort, scientists have combined sensitive experimental measurements with fi rst principle electronic structure calculations to measure, and to really understand, the structural and bonding parameters of uranyl, the most common oxidation state of uranium in systems containing water.
The insights were achieved by PNNL scientist Bert de Jong and associates Gary Groenewold of Idaho National Laboratory and Michael Van Stipdonk of Wichita State University, employing the supercomputing resources of the William R.

Errors in the genetic code can give rise to cancer and a host of other diseases, but finding these errors can be more difficult than looking for the proverbial needle in the haystack. Now, scientists at Johns Hopkins have uncovered how the tiny protein-machines in cells tasked to search for such potentially life-threatening genetic damage actually recognize DNA errors.
Appearing online next week in Nature, the Hopkins team describes how the UDG enzyme (for uracil DNA glycosylase) scrutinizes the shape of DNA building blocks by holding onto them and testing their fit into a specially sized pocket. The UDG pocket holds onto mistakes only — the enzyme loses its grip on the right building blocks, which fall back in line with the rest of the DNA.

Do bats use their ultrasonic echolocation calls to recognize their own species?
A new study in the Journal of Biogeography by Danilo Russo and colleagues suggests that this is certainly the case for Rhinolophidae - horseshoe bats. These bats find their way in the dark and detect insect prey by emitting long ultrasound calls mainly made of a constant frequency. Different rhinolophid species show different frequency values. It has been proposed that such differences are large enough to allow recognition of conspecifics.
The study proved that in Sardinia, Mediterranean (Rhinolophus euryale) and lesser (R.. hipposideros) horseshoe bats show divergence in call frequency, spacing them out more than their conspecifics living in peninsular Italy (i.e. on the mainland).

Scientists at Pacific Northwest National Laboratory have discovered a way to increase the sensitivity of test strips that will enable creation of a portable biosensor that can address a major concern associated with incidents involving chemical or nerve agents - the need to quickly distinguish between individuals who have been exposed and the "worried well."
The sensor components resemble a pregnancy test strip and a small glucose testing meter. Its development will be discussed by principal investigator Yuehe Lin at the national meeting of the American Chemical Society.
Every disease has biomarkers, a change in the proteins that announces something is wrong.

Combine a mechanical arm with a miniature rocket motor: The result is a prosthetic device that is the closest thing yet to a bionic arm.
A prototype of this radical design has been successfully developed and tested by a team of mechanical engineers at Vanderbilt University as part of a $30 million federal program to develop advanced prosthetic devices.
“Our design does not have superhuman strength or capability, but it is closer in terms of function and power to a human arm than any previous prosthetic device that is self-powered and weighs about the same as a natural arm,” says Michael Goldfarb, the professor of mechanical engineering who is leading the effort.

Michael Goldfarb, professor of mechanical engineeri

Without the heartbreak of ended relationships, half of popular music would cease to exist. Everyone has had one but it turns out it probably wasn't so bad - especially if you thought it would be horrible.
A new Northwestern University study shows that lovers, even those madly in love, do much better following a breakup than they imagined they would.
In other words, participants who forecast how badly they would feel over a breakup with a partner actually felt much less distress than they had predicted in the days prior to the relationship’s demise.

In 17th century Rome, the Baroque painter Orazio Gentileschi gave all his children the finest art education available. But only one of them—his daughter Artemisia—developed into an artist. In fact, Artemisia matched and surpassed her father's skills, and became the first female member of the Academy of Design in Florence and the only woman to follow and innovate upon the tradition of painting established by Caravaggio.
What creates a great artist like Gentileschi, Van Gogh or Manet? Talent or training?

Chemical engineers at Purdue believe they have discovered a fundamental flaw in the conventional view of how liquids form bubbles that grow and turn into vapors and that their findings cast into doubt some aspects of a theory dating back to the 1920s, said David S. Corti, an associate professor of chemical engineering at Purdue University.
The research could lead to a more precise understanding of the "phase transition" that takes place when bubbles form, grow and then become a vapor, which could, in turn, have implications for industry and research, Corti said.

Dozens of scientists from several countries gathered at the University of Alaska Fairbanks to discuss the latest findings on noctilucent clouds and other phenomena of the earth’s upper atmosphere during the Eighth International Workshop on Layered Phenomena in the Mesopause Region.
“The question which everyone in Alaska is dealing with is what are the symptoms of climate change and, as in medicine, how do these symptoms reflect the underlying processes,” said Richard Collins, a researcher at the Geophysical Institute at the University of Alaska Fairbanks. “It is believed that [these clouds] are an indicator of climate change.”
Noctilucent clouds form under conditions that counter common logic. They only form in the summer, when solar radiation is most intense, Collins said.