A new cancer vaccine platform works by enhancing the ability of the immune system to recognize cancer by leveraging anti-viral memories it already has - due to the COVID-19 pandemic, the worst outbreak of the last 70 years.
A situation in which wages increase 2.3% and prices increase 3.1% is equivalent to a situation in which wages fall by 0.8% at constant prices. Though the two scenarios are equivalent in real terms there are people who perceive these situations differently. These people are said to be prone to 'money illusion.'
It has been commonly thought that the impact of irrational behavior is limited in markets because “smart agents” can take advantage of irrational traders.
Female rhesus monkeys use special vocalizations while interacting with infants, the way human adults use motherese, or “baby talk,” to engage babies’ attention, new research at the University of Chicago shows.
“Motherese is a high pitched and musical form of speech, which may be biological in origin,” said Dario Maestripieri, Associate Professor in Comparative Human Development at the University.
Huntington's is an inherited degenerative neurological disease that affects up to 8 people out of every 100,000 in Western countries. Any person whose parent has Huntington's has a 50-50 chance of inheriting the faulty gene that causes it and everyone with the defective gene will, at some point, develop the disease.
It is characterized by a loss of neurons in certain regions of the brain and progressively affects a sufferer’s cognition, personality and motor skills. In its later stages, sufferers almost certainly require continual nursing care.
Scientists have shown in literally thousands of studies that the p53 gene deserves its reputation as “the guardian of the genome.” It calls to action an army of other genes in the setting of varied cell stresses, permitting repair of damaged DNA or promoting cell death when the cell damage is too great. A key net effect of p53’s action is to prevent development of cancerous cells.
Now, University of Michigan Medical School scientists provide the most thorough evidence yet that p53 also regulates a trio of genes from the realm of so-called “junk” genes — the roughly 97 percent of a cell’s genetic material whose function is only beginning to be understood.
One of the strangest and most endangered birds in the world, the kakapo, is being brought back from the brink of extinction with the help of scientists from the University of Glasgow.
The largest of all parrot species, flightless, nocturnal and plant-eating, the kakapo used to be found all over New Zealand. But ecological changes, habitat clearance and the introduction of predatory mammals combined to cause a catastrophic decline in numbers to only 51 in 1995.
Another factor in their near extinction is that kakapo breed infrequently. This is because they rear their young on the fruits of native trees. These trees - pink pine and rimu – only fruit every 2-6 years and kakapo only breed on those occasions.
A new interpretation of data from NASA’s Viking landers indicates that 0.1% of the Martian soil tested could have a biological origin.
Dr Joop Houtkooper of the University of Giessen, Germany, believes that the subfreezing, arid Martian surface could be home to organisms whose cells are filled with a mixture of hydrogen peroxide and water. Dr Houtkooper described how he has used data from the Gas Exchange (GEx) experiment, carried by NASA’s Viking landers, to estimate the biomass in the Martian soil.
Viking 2 lander image looking back across the craft. Dark boulders are prominent against the reddish soil. The landing site, Utopia Plantia, is a region of fractured plains.
Observations of solar flares by spacecraft at Mars, Venus and the Earth show that eruptions on the far side of the Sun may affect our “space weather” back on Earth.
In December 2006, a series of solar flares produced in a single active region were observed from three different points, each approximately 120 degrees apart.
Opponents of gay marriage in the United States state that nuclear families have always been the standard household form. Turns out this may not be true. While gay marriage itself may not have happened in medieval times there is evidence that homosexual civil unions did and that could lend important historical insight to the debate.
Allan A.
Katherine Franz, an assistant chemistry professor at Duke University, says the key to battling neurological diseases like Parkinson's and Alzheimer's diseases may lie in binding up iron and then separating the good from the bad.
Her approach, with graduate student Louise Charkoudian, is to formulate sensitive chemical sentinels they call "pro-chelators." Those are metal-binding agents wrapped in chemical "cages" so they can enter the brain and wait in reserve until they encounter a site of potential damage.
Such a site contains both iron and the molecule hydrogen peroxide. The reaction between these two players -- known as a "Fenton reaction" -- can lead to the production of a highly reactive oxygen-containing chemical group called a hydroxyl radical, Franz said.
The research group of Prof. Dr. Magdalena Götz at the Institute of Stem Cell Research of the GSF – National Research Centre for Environment and Health, and the Ludwig Maximilians University, Munich, has achieved an additional step for the potential replacement of damaged brain cells after injury or disease: functional nerve cells can be generated from astroglia, a type of supportive cells in the brain by means of special regulator proteins.
The majority of cells in the human brain are not nerve cells but star-shaped glia cells, the “astroglia”. "Glia means 'glue'," explains Götz. "As befits their name, until now these cells have been regarded merely as a kind of 'putty' keeping the nerve cells together."
The “world’s fattest mice” can overeat without developing insulin resistance or diabetes thanks to a glut of adiponectin, a hormone that controls sensitivity to insulin, and a lack of leptin, a hormone that curbs appetite - a dichotomy that helps explain why not all obese people are diabetic, a UT Southwestern Medical Center researcher has found.
Consuming excess calories usually spurs insulin resistance and diabetes, but the new findings demonstrate how mice can store excess calories in fat tissue instead of in liver, heart or muscle tissue – places where excess fat can lead to inflammation, diabetes and heart disease. The mice get morbidly obese, but are insulin-sensitive with normal blood-glucose levels.
Analysis of the chemical make up of two asteroids in the outer asteroid belt has thrown the classification system for these small bodies, which orbit between Mars and Jupiter, into disorder.
Dr Rene Duffard, said, “We appear to have detected basalt on the surface of these asteroids, which is very unusual for this part of the asteroid belt. We do not know whether we have discovered two basaltic asteroids with a very particular and previously unseen mineralogical composition or two objects of non basaltic nature that have to be included in a totally new taxonomic class.”
The presence of basalt means that the asteroid must have melted partially at some time in the past, which implies that it was once part of a larger body which had internal heating processes.
