Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
Researchers employing an extensive analysis of genomic information have identified micro RNA 506 (miR-506) as a potential therapeutic candidate for advanced or metastatic ovarian cancer
situations. This high-risk cohort of ovarian cancer patients can be tested in mouse models of the disease to try and find better treatments.
Researchers have discovered 24 new genes that cause refractive errors and myopia, commonly known as short-sightedness.
Humans have an unclear number of genes - ab initio gene finding and comparative gene finding yield different totals (see the Human Genome Project for details) - but it is likely in the low 20,000s and those genes make nearly as many proteins. The functions of most genes have not been fully determined, but knowing what a particular gene does could obviously help researchers understand disease processes and identify targets for new drugs.
Media is increasingly filled with miracle vegetable and scare journalism stories, all that say they are based on scientific studies. When faced with a headline that suggests an Alzheimer's drug increases the risk of heart attack or that watching TV is bad for children's mental health, or that pesticides are causing a decline in bee populations, how do people know which can be taken seriously and which are just 'scares'? Checking for peer review is a good first step. The 'alar scare' over apples in the US, for example, was produced by a shoddy activist group and then promoted by health and science journalists who latched onto the outrageous claim of the week. It would never have passed peer review in a legitimate journal.
RNL BIO CO LTD has announced the filing of an Investigational New Drug (IND) application with the Korean Food and Drug Administration (KFDA) to initiate clinical trials phase II and III assessing the company's RNL-Astrostem(TM) stem cell drug in patients with cerebral palsy.
Cerebral Palsy is caused by non-progressive brain damage from single or multiple defect(s) on the nerve/muscular system and results in disorder in motion and sensory integration. According to Health Insurance Review and Assessment Service, the prevalence of cerebral palsy is 3.5 per 1000 male to 2.8 per 1000 female children, averaged at 3.2 per 1000 children, which is expected to increase due to reduction of premature death.
Maybe it is not just sentimental. Perhaps the connection to "man's best friends" is literally in our heads.
Skull shape is a complex trait, involving multiple genes and their interactions. Thanks to standardized canine breeding, which documents more than 400 breeds worldwide, and their distinct morphological features, researchers can disentangle traits such as skull shape, which is often a breed-defining variation.
Adding fruits and vegetables to diets may help protect the kidneys of patients with chronic kidney disease (CKD) with too much acid build-up, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). This is good news, since it has also been shown that frequent dialysis poses risks for kidney patients.
Compared with standard dialysis, frequent hemodialysis, requires accessing the blood more often than conventional hemodialysis, can cause complications related to repeated access to the blood, requiring patients to undergo more repair procedures to the site through which blood is removed and returned, according to a study in the Journal of the American Society of Nephrology (JASN).
Requiring individuals to pay a premium for public health insurance coverage will counteract the coverage effects of expanding eligibility for public health insurance programs to higher income families, according to a paper in the journal Health Services Research.
Estimating using their numerical model, researchers from Georgetown University School of Nursing&Health Studies (NHS), University of California at Los Angeles (UCLA), and Columbia University examined how income eligibility thresholds and premium contribution requirements associated with public health insurance programs affect children's health insurance coverage outcomes.
At the start of this year, a controversial feature of President Obama's Affordable Care Act (ACA) went into effect.
Under the ACA, medical devices companies will have to pay new tax of 2.3% on gross sales. While medical devices companies have opposed the tax, saying it will hurt research and development activities, proponents of ACA say, of course, that more taxes will be good for them. In progressive economics, companies such as Hologic Inc. and St. Jude Medical Inc. will get more customers due to their higher taxes and that will boost sales of medical devices.
Two new studies look for ways to improve surgical treatment for a debilitating condition called neurogenic thoracic outlet syndrome, which is caused by compressed nerves in the neck and shoulder and causes pain, numbness or tingling in the shoulder, arm or hand.
It is most common in baseball pitchers and other elite athletes. Patients often describe pain and tension in the neck and upper back, numbness and tingling in the fingers, headaches and perceived muscle weakness in the affected limb.
Researchers at the Universities of Edinburgh and Southampton have brought the science of repairing broken bones into the 21st century, using adult bone stem cells combined with a degradable lightweight plastic that encourages real bone to re-grow.
