Scientists have reported that an experimental vaccine targeting one of the most common genetic drivers of pancreatic cancer, called mutant KRAS, is safe and generated a durable immune responses aimed at preventing the cancer.
In the year 1006 a new star was seen in the southern skies and widely recorded around the world. It was many times brighter than the planet Venus and may even have rivaled the brightness of the Moon. It was so bright at maximum that it cast shadows and it was visible during the day. More recently astronomers have identified the site of this supernova and named it SN 1006. They have also found a glowing and expanding ring of material in the southern constellation of Lupus (The Wolf) that constitutes the remains of the vast explosion.
The expanding debris of exploded stars produces some of the fastest-moving matter in the universe, according to a new paper. Supernova remnants accelerate cosmic rays to incredible speeds.
Cosmic rays are subatomic particles that move through space at almost the speed of light. About 90 percent of them are protons, with the remainder consisting of electrons and atomic nuclei. In their journey across the galaxy, the electrically charged particles are deflected by magnetic fields. This scrambles their paths and makes it impossible to trace their origins directly. Through a variety of mechanisms, these speedy particles can lead to the emission of gamma rays, the most powerful form of light and a signal that travels to us directly from its sources.
Why are physicists thick-skinned but biologists run for the hills when the comment trolls invariably appear? It may help to be arcane and complex - it's harder to troll hard sciences. Everyone feels like they know some biology but good luck to casual readers trying to debunk rare B_s decays in a high energy physics paper.
Researchers have discovered that many women with low-grade serous carcinoma of the ovary or peritoneum have seen their tumors stabilize or shrink after taking a regular dose of the compound selumetinib, according to a paper in The Lancet Oncology which show that selumetinib targets a mutation in the MAPK pathway for patients with low-grade serous carcinoma, allowing for treatment on previously chemoresistant tumors.
"This is a potentially important breakthrough for the Gynecologic Oncology Group," said first author John Farley, MD, a gynecologic oncologist at St. Joseph's Hospital.
An animal model of recent human evolution found that a single mutation produced several traits common in East Asian people, from thicker hair to denser sweat glands. They also modeled the spread of the gene mutation across Asia and North America, concluding that it most likely arose about 30,925 years ago in what is today central China.
Previous research identified the mutation as a strong candidate for positive selection. That is, evidence within the genetic code suggested the mutant gene conferred an evolutionary advantage, though what advantage was unclear.
2012 was the 40th anniversary since President Richard Nixon signed the Clean Water Act and established regulations for the discharge of pollutants to waterways - and even lets the government declare water itself as a pollutant.
Despite sewage treatment plants becoming more widespread, sewage can still be a major source for both naturally occurring hormones found in the environment and from both pharmaceuticals and personal care products (PPCPs).
Lulu, the iOS and Android app for reviewing and objectifying men, had a good first week, reaching the Top 20 in the U.S App. store with over 100,000 downloads.
On Lulu, girls anonymously ridicule and rate men on appearance, humor, manners, ambition, first kiss, sex, and commitment. So if you want to know if that guy you met has a #CleanBathroom or is #CheaperThanABigMac, this is for you.
Like 75 percent of online gamers, it helps to at least pretend to be a woman. If you admit to being a man, or your Facebook login is a man, you get the rejection: "Dude, you're a dude." Perhaps due to keeping out icky men, so far people are being nice. The worst condemnation a man can get, though, is an ex-girlfriend saying he is a keeper...for someone else.
Like the term 'junk DNA', the idea of 'primitive' reflexes is contextually confusing to some people outside biology. In reality, after millions of years of evolution, even a primitive reflex is sophisticated.
New satellite images show that the ozone hole over Antarctica in 2012 was the smallest seen in the past decade. Long-term observations show that Earth’s ozone has been strengthening. The ozone sensor on Europe’s MetOp weather satellite continues the long-term monitoring of atmospheric ozone started by its predecessors on the ERS-2 and Envisat satellites.
Genome sequences of seven well-studied ant species give researchers a detailed look at molecular mechanisms - including what may be a basis for complex behavioral differences in two worker castes in the Florida carpenter ant, Camponotus floridanus - basically, epigenetics.
Which is more important, feeling close to your romantic partner or whether you are as close as you want to be, even if that's really not close at all?
Outside the social sciences, the answer is obvious. But in social psychology, it is a paper in time for Valentine's Day. Let's go to the surveys.
New data from NASA's Chandra X-ray Observatory suggest a highly distorted supernova remnant called W49B may contain the most recent black hole formed in the Milky Way galaxy.
W49B
appears to be the product of a rare explosion in which matter is ejected at high speeds along the poles of a rotating star and is about a thousand years old (as seen from Earth) and is located about 26,000 light-years away.
Usually when a massive star runs out of fuel, the central region of the star collapses, triggering a chain of events that quickly culminate in a supernova explosion. Most of these explosions are generally symmetrical, with the stellar material blasting away more or less evenly in all directions.
