Why Both Stimulating And Blocking GLP-1R Helps People Lose Weight
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Understanding which brain circuits respond to weight loss medications and how they behave could lead to better weight loss with fewer side effects.
Contrary to conservative wisdom, exercising up to the end of pregnancy has no harmful effect on the health of the mother or child, and may even be beneficial for both, indicates a study published in the International Journal of Obesity.160 healthy women between the ages of 25 and 35 took part in the study, all of whom had sedentary habits and no risk of premature birth. Of this group of women, half followed an exercise regime under the supervision of experts in Physical Activity and Sports Science in collaboration with the Gynaecology and Obstetrics Unit of Hospital Severo Ochoa in Madrid.
A team of researchers said this week that they may have identified the genes responsible for bipolar disorder in children. Their study, published in BMC Psychiatry, implicates malfunctioning circadian clock genes, four alterations of the RORB gene to be specific, in the development of the disorder. Scientists studied the RORA and RORB genes of 152 children with Bipolar and 140 control children. They found four alterations to the RORB gene that were positively associated with being bipolar. "Our findings suggest that clock genes in general and RORB in particular may be important candidates for further investigation in the search for the molecular basis of bipolar disorder," explained co-author Alexander Niculescu.
The controversy surrounding prescription drug advertising is immense. Advocates for prescription drug direct-to-consumer advertising (DTCA) claim that it educates consumers, improves the quality of care and contributes to better patient adherence. While opponents argue that it leads to inappropriate prescribing and portrays non-medical problems as treatable medical illnesses.Thanks to a new paper calling for stricter federal regulation of DTCA, the policy debate over the practice is certain to intensify even more. Soon to appear in the American Journal of Public Health, the study suggests that while there are some benefits stemming from (DTCA), there are significant risks that are magnified by its prominence.
Enhancing the effects of dopamine influences how people make life choices by affecting expectations of pleasure, according to new research from the UCL Institute of Neurology. Published today in Current Biology, the study confirms an important role for dopamine in how human expectations are formed and how people make complex decisions. It also contributes to an understanding of how pleasure expectation can go awry, for example in drug addiction. The study builds on earlier research which used brain imaging as participants imagined holiday destinations. An area of the brain called the straitum tracked expectations and the
The concept of altruism, a selfless concern for the welfare of others, a traditional virtue in many cultures and a core aspect of various religious traditions, has long been debated in philosophical circles. More recently, evolutionary biologists have joined the debate, saying that altruism may have evolved because any action that improves the likelihood of a relative's survival and reproduction increases the chance of an individual's DNA being passed on.
With the COP15 conference fast approaching, the world's political leaders are gearing up to hash out a global agreement that will save us from ever increasing greenhouse gas emissions and the unstoppable climate change that will follow.New research published this week in Geophysical Research Letters, however, may complicate their plans. The new research, conducted by a professor of Earth Science at the University of Bristol, shows that the balance between the airborne and the absorbed fraction of CO2 has stayed approximately constant since 1850, despite emissions of CO2 having risen from about 2 billion tons a year in 1850 to 35 billion tons a year now.
After the successful introduction of myspace, facebook, twitter and however many other social networking sites that now exist, researchers at London's Natural History Museum have created a social networking tool called 'Scratchpads' just for natural historians. The platform is designed to get specialists together to share their data and prevent the discipline from being buried under a landslide of painstakingly collected data that isn't always used.
If you're sore from a strenuous workout or your thumb is pulsating because you hit it with a hammer, look at a pretty picture or listen to your favorite song. It just might help you cope with whatever unpleasant feeling you're experiencing . That's the conclusion of a study published in the Proceedings of the National Academy of Sciences that looked at the connection between human emotions and physical pain. "Emotions – or mood – can alter how we react to pain since they're interlinked," says lead author Mathieu Roy. "Our tests revealed when pain is perceived by our brain and how that pain can be amplified when combined with negative emotions."
Scientists say they can now tell the condition of an old book by its odor. In a report published in Analytical Chemistry, a team of researchers describe development of a new test that can measure the degradation of old books and precious historical documents on the basis of their aroma. The non-destructive "sniff" test could help libraries and museums preserve a range of prized paper-based objects, some of which are degrading rapidly due to advancing age, the scientists say.The new technique — an approach called "material degradomics" — analyzes the gases emitted by old books and documents without altering the documents themselves. The scientists used it to "sniff" 72 historical papers from the 19th and 20th centuries.
If rehospitalization is considered when grading health care, America's system is not all it is cracked up to be. Proof? New evidence indicates almost a quarter of heart failure patients with Medicare are back in the hospital within a month after discharge, researchers report today in Circulation: Heart Failure. Each year, from 2004 through 2006, more than a half million Medicare recipients over age 65 went to the hospital for heart failure and were discharged alive. And each year, about 23 percent returned to the hospital within 30 days – signaling a need to improve care, researchers said. Readmission rates for all causes were almost identical all three years.
With Tropical Storm Ida currently dumping rain and high winds in the southeast we wanted to talk about coastal hazards. Coastal hazards along America's shorelines threaten a significant percentage of the U.S. population. Here is a quick beach quiz to find out how much
you know about your risks.1: What is a coastal hazard? a) Windb) Waves c) Flooding
d) All of the abovee) None of the above 2: How many miles of shoreline does the United States have exposed to coastal
hazards?a) 7,000 b) 9,000c) 5,500d) 7,500
This week, scientists from Australia and the UK are taking a break from their professional research to wave their fists angrily at the alcohol industry. In hopes of reducing alcohol abuse, they are calling for a new approach to the debate over whether alcohol industry sponsorship of sports increases drinking among sports participants. They want to shift the burden of proof to the alcohol industry.The debate over sports sponsorship saw renewed activity last year when the findings of a 2008 New Zealand study among sports participants showed that those who received alcohol industry sponsorship – especially in the form of free or discounted alcohol – drank more heavily than those not in receipt of such sponsorship.