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Doctors Facing Complaints Get Severe Depression And Suicidal Thoughts

Doctors Facing Complaints Get Severe Depression And Suicidal Thoughts

UK doctors subject to complaints procedures are at significant risk of becoming severely depressed and suicidal, reveals research published in the online journal BMJ Open.
Those referred to the UK professional regulator, the General Medical Council, seem to be most at risk of mental ill health, the findings suggest.
The researchers base their findings on an anonymised online survey of more than 95,000 UK doctors in 2012, all of whom were members of the British Medical Association (BMA).

What Role Do Cytokines Have In Breast Cancer?

What Role Do Cytokines Have In Breast Cancer?

Emerging data on the role of inflammation and the immune system in the development, growth, and spread of breast tumors have focused increased attention on the role cytokines such as interleukin and transforming growth factor-β play in breast cancer initiation, protection, and metastasis.
A comprehensive overview of this new knowledge and its potential to lead to novel therapeutic approaches is presented in a Review article in Journal of Interferon & Cytokine Research.

Personalized Treatment For Intellectual Disability Developed

Personalized Treatment For Intellectual Disability Developed

Researchers have created a new approach that protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels. The method focuses on treating the effects of mutations to a gene known as Syngap1. Damaging mutations in Syngap1 that reduce the number of functional proteins are one of the most common causes of sporadic intellectual disability and are associated with schizophrenia and autism spectrum disorder.

Counterintuitive: Anti-Inflammatory Protein May Trigger Alzheimer's Disease Plaque

Counterintuitive: Anti-Inflammatory Protein May Trigger Alzheimer's Disease Plaque

Inflammation has long a target in Alzheimer's disease studies so a new finding in Neuron is counterintuitive. In the study, researchers hace uncovered the mechanism by which anti-inflammatory processes may trigger the disease and this anti-inflammatory process might actually trigger the build-up of sticky clumps of protein that form plaques in the brain. These plaques block brain cells' ability to communicate and are a well-known characteristic of the illness.
The finding suggests that Alzheimer's treatments might need to be tailored to patients depending on which forms of Apolipoprotein E, a major risk factor for Alzheimer's disease, these patients carry in their genes.

New Bacterial Language Discovered

New Bacterial Language Discovered

Bacteria communicate using chemical signals and now scientists have described a previously unknown communication pathway that appears to be widely distributed - and even leads to pathogens.
The investigation of bacterial communication is valuable because those pathways are a possible therapeutic target for new medicines. If the relevant communication options are prevented, the bacteria cannot develop their pathogenic properties.

Jupiter's Triple Transit For 2015

Jupiter's Triple Transit For 2015

Jupiter's moons are giving us a show not seen since 2013: The orbital path of the moons is tilting edge-ion to the Earth and the sun, making it possible to watch the moons pass in front of each other, an occultation, or pass through another moon's shadow, an eclipse, and even cast tiny black shadows onto Jupiter.

The Coupler - New Implant Lowers Blood Pressure After Outpatient Procedure

The Coupler - New Implant Lowers Blood Pressure After Outpatient Procedure

A new device developed by ROX Medical and named the 'Coupler' is a paper clip-sized implant which is inserted between the artery and vein in the upper thigh that has been shown to significantly lower blood pressure among patients with uncontrolled high blood pressure, compared to those treated with usual drug measures.  It can be inserted in a procedure lasting around 40 minutes under local anesthetic.  

BPA Exposure Affects Heart Health Of Male And Female Mice Differently

BPA Exposure Affects Heart Health Of Male And Female Mice Differently

Heart function and blood pressure in mice exposed to bisphenol A (BPA) from birth though young adulthood are affected differently in males and females, with females at greater risk of damage from stress, a study from a University of Cincinnati (UC) researcher has found.
A research team led by Scott Belcher, PhD, professor of pharmacology and cell biophysics, Robin Gear, principal research assistant, and Eric Kendig, PhD, former UC postdoctoral fellow, found that in young BPA exposed female mice, the heart is more sensitive to stress-induced ischemic damage in a way not observed in untreated female mice.

Inventors Are Not As Paranoid About Patents As People Think

Inventors Are Not As Paranoid About Patents As People Think

Common wisdom and prior economic research suggest that an inventor filing a patent would want to keep the technical know-how secret as long as possible. But a new study of nearly 2 million patents in the United States shows that inventors are not as concerned with secrecy as previously thought. Researchers found that since 2000, most inventors when given the choice opted to disclose information about their patents before patent approval - even small inventors - and this disclosure correlates with more valuable patents.

Antiquity Of Dairy Farming In Ireland Revealed

Antiquity Of Dairy Farming In Ireland Revealed

As dairy farmers across Europe anxiously await the lifting of EU milk quotas in April this year, new research from the University of Bristol, UK has revealed the antiquity of dairy farming in a region famous for its dairy exports: Ireland.
Research published today in the Journal of Environmental Archaeology shows that dairying on the island goes back approximately 6,000 years, revealed through traces of ancient dairy fats found in pots dating to around 4,000 to 2,500 BC.

2,500-year-old Pythagorean Theorem Helps Determine When Patient Recovery Has Occurred

2,500-year-old Pythagorean Theorem Helps Determine When Patient Recovery Has Occurred

A medical researcher at the University of Warwick has found the 2,500 year-old Pythagoras theorem could be the most effective way to identify the point at which a patient's health begins to improve.
In a new paper, Dr Rob Froud from Warwick Medical School at the University of Warwick and Gary Abel from the University of Cambridge made the discovery after looking at data from ROC (Receiver Operating Characteristic) curves.
These curves were initially developed during World War II for the analysis of signals to help operators decide whether a blip on the screen was an enemy target or allied forces ships or aircrafts. In the 1980s, the curves were adopted by epidemiologists to help them decide at what point an individual has recovered from an illness.

3 Million Years Ago, Pre-Humans May Have Used Hands Just Like Modern Humans

3 Million Years Ago, Pre-Humans May Have Used Hands Just Like Modern Humans

Social scientists believe that pre-Homo human ancestral species, such as Australopithecus africanus, used human-like hand postures much earlier than was previously thought.The authors say they have the first archaeological evidence for stone tool use among fossil australopiths 3-2 million years ago. The distinctly human ability for forceful precision (e.g. when turning a key) and power "squeeze" gripping (e.g. when using a hammer) is linked to two key evolutionary transitions in hand use: a reduction in arboreal climbing and the manufacture and use of stone tools. However, it is unclear when these locomotory and manipulative transitions occurred.