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Brain structure changes years before memory loss begins

Brain structure changes years before memory loss begins

People who develop dementia or Alzheimer's disease experience brain structure changes years before any signs of memory loss begin, according to a study published in the April 17, 2007, issue of Neurology®, the scientific journal of the American Academy of Neurology. Researchers say these findings may help identify people at risk of developing mild cognitive impairment (MCI), which leads to Alzheimer's disease.

Joint Genome Institute releases Genome Data Management System IMG 2.1

Joint Genome Institute releases Genome Data Management System IMG 2.1

As interest in the rising number of newly characterized microbial genomes mounts, powerful computational tools become critical for the management and analysis of these data to enable strategies for such challenges as harvesting the potential of carbon-neutral bioenergy sources and coping with global climate change.
The Integrated Microbial Genomes (IMG) data management system developed by the U.S. Department of Energy Joint Genome Institute (DOE JGI) addresses this challenge with the release of version 2.1. Released on the two-year anniversary of its launch, the content of IMG 2.1 is updated with new microbial genomes from National Center for Biotechnology Information’s (NCBI) Reference Sequence collection (RefSeq) latest release, Version 21.

Fiber-optic light source promises improvements in food inspection

Fiber-optic light source promises improvements in food inspection

A new light source based on fiber-optic technology promises to improve the inspection of food, produce, paper, currency, recyclables and other products. New research revealing this technology will be presented at the Optical Fiber Communication Conference and Exposition/National Fiber Optic Engineers Conference (OFC/NFOEC), being held March 25-29 in Anaheim, Calif.
Currently, industrial processes for inspecting foodstuffs and other items often use "line-scan" cameras, which record images of objects one line at a time, just as fax machines scan documents on a line-by-line basis. Rapid electronic processors then detect whether there are any problems with the items and instruct mechanical actuators (such as air jets) to separate out unsatisfactory items.

Warming oceans threaten Antarctic glaciers

Warming oceans threaten Antarctic glaciers

Scientists have identified four Antarctic glaciers that pose a threat to future sea levels using satellite observations, according to a study published in the journal Science.
Experts from the University of Edinburgh and University College London determined the effect that Antarctica and Greenland were having on global sea level in a comprehensive evaluation of the Earth’s ice sheets. They found that together these two ice-sheets were responsible for a sea level rise of 0.35 millimetres per year over the past decade – representing about 12 per cent of the current global trend.
However, despite recent attention that has focused on the importance of the Greenland ice sheet, the research shows that its glaciers are changing too erratically to establish a trend with confidence.

Researchers use poliovirus to destroy neuroblastoma tumors in mice

Researchers use poliovirus to destroy neuroblastoma tumors in mice

The cause of one notorious childhood disease, poliovirus, could be used to treat the ongoing threat of another childhood disease, neuroblastoma. In the March 15 issue of Cancer Research, researchers from Stony Brook University report that an attenuated -- or non-virulent -- form of poliovirus is effective in obliterating neuroblastoma tumors in mice, even when the mice had been previously vaccinated against the virus.
By its nature, poliovirus destroys the cells it infects in an attempt to replicate copies of itself. When released from the cells it kills, the replicated particles then attack surrounding cells.

Video games shown to improve vision

Video games shown to improve vision

According to a new study from the University of Rochester, playing action video games sharpens vision. In tests of visual acuity that assess the ability to see objects accurately in a cluttered space, game players scored higher than their non-playing peers.
"Action video game play changes the way our brains process visual information," says Daphne Bavelier, professor of brain and cognitive sciences at the University of Rochester.

Apple consumers reap heart-health benefits thanks to flavonoid content, says new research

Apple consumers reap heart-health benefits thanks to flavonoid content, says new research

Apples may prove to be a winner when it comes to reducing the risk of heart disease, says a new study of more than 34,000 women. In this study, flavonoid-rich apples were found to be one of three foods (along with red wine and pears) that decrease the risk of mortality for both coronary heart disease (CHD) and cardiovascular disease (CVD) among post-menopausal women, The findings were published in the March 2007 American Journal of Clinical Nutrition.
Women of all ages are encouraged to consume more fruit and vegetables, including apples and apple products, for heart health. However, this study focused on postmenopausal woman, a group becoming more aware of the risk for heart disease.

New reagent delivers a chemical breakthrough at FSU

New reagent delivers a chemical breakthrough at FSU

"Build a better mousetrap," the saying goes, "and the world will beat a path to your door." In the complex field of organic chemistry, that path leads to Florida State University, where a newly developed substance could make the jobs of scientists throughout the world a little easier as they work to develop new drugs and other chemicals that benefit humanity.
Researchers from the Dudley Laboratory at FSU have invented a reagent — a substance used in a chemical reaction to detect, measure, examine or produce other substances — that can trap specific regions of complex molecules in such a way that those molecules can be released at a later time.

UNC scientists discover cellular 'SOS' signal in response to UV skin damage

UNC scientists discover cellular 'SOS' signal in response to UV skin damage

New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer.
The study, which appears in the advance online edition of the journal Molecular and Cellular Biology, indicates that two proteins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation.
Ultraviolet radiation in sunlight damages the DNA in skin cells. If left unrepaired by the cell, this damage can turn into mutations that lead to cancer. Before cells divide, they must replicate, or copy, their DNA to form new daughter cells.

Mars Express radar gauges water quantity around Mars south pole

Mars Express radar gauges water quantity around Mars south pole

This new estimate comes from mapping the thickness of the dusty ice by the Mars Express radar instrument that has made more than 300 virtual slices through layered deposits covering the pole. The radar sees through icy layers to the lower boundary, which in places is as deep as 3.7 kilometres below the surface.
"The south polar layered deposits of Mars cover an area as wide as a big portion of Europe. The amount of water they contain has been estimated before, but never with the level of confidence this radar makes possible," said Dr. Jeffrey Plaut of NASA's Jet Propulsion Laboratory, Pasadena (California), co-Principal Investigator for the radar and lead author of the study.

Global 'Sunscreen' Has Likely Thinned - NASA

Global 'Sunscreen' Has Likely Thinned - NASA

A new NASA study has found that an important counter-balance to the warming of our planet by greenhouse gases – sunlight blocked by dust, pollution and other aerosol particles – appears to have lost ground.
The thinning of Earth’s "sunscreen" of aerosols since the early 1990s could have given an extra push to the rise in global surface temperatures. The finding, published today in the journal Science, may lead to an improved understanding of recent climate change. In a related study published last week, scientists found that the opposing forces of global warming and the cooling from aerosol-induced "global dimming" can occur at the same time.

RNA enzyme structure offers a glimpse into the origins of life

RNA enzyme structure offers a glimpse into the origins of life

Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. Their results provide insight into what may have been the first self-replicating molecule to arise billions of years ago on the evolutionary path toward the emergence of life.
In all forms of life known today, the synthesis of DNA and RNA molecules is carried out by enzymes made of proteins. The instructions for making those proteins are contained in genes made of DNA or RNA (nucleic acids). The circularity of this process poses a challenge for theories about the origins of life.
"Which came first, nucleic acids or proteins?