News Articles

New non-toxic and targeted therapies for metastatic breast and ovarian cancers may now be possible, thanks to a discovery by a team of researchers at the University of British Columbia.
In a collaboration between UBC stem cell and cancer scientists, it was found that a protein called podocalyxin – which the researchers had previously shown to be a predictor of metastatic breast cancer – changes the shape and adhesive quality of tumour cells, affecting their ability to grow and metastasize. Metastatic cancer is invasive cancer that spreads from the original site to other sites in the body.
The discovery demonstrated that the protein not only predicted the spread of breast cancer cells, it likely helped to cause it.

To address the high rate of multiple births resulting from in-vitro-fertilization (IVF), researchers at Yale School of Medicine and McGill University have developed a procedure that estimates the reproductive potential of individual embryos, possibly leading to a decrease in multiple-infant births and a higher success rate in women undergoing IVF.
Over 100,000 in-vitro fertilization procedures are performed each year in the United States. In 2002, 3.1 embryos on average were transferred in IVF cycles, but only 34.3 percent resulted in pregnancies. Of those successful pregnancies, 29 percent resulted in multiple births. These statistics remained unchanged within the last decade suggesting that an improvement is needed over the current methodology used for embryo evaluation.

A federal law requiring publicly traded firms to disclose whether they have adopted codes of ethics for their senior financial officers may be useful, but a Penn State researcher says its impact is often limited.
A firm's board of directors needs to be the driving force behind creating and implementing the program in most cases for it to truly be successful.
"According to my research, firms with ethics programs overseen by their boards of directors disclose more credible financial information—as perceived by financial analysts—than do firms having ethics programs not overseen by their boards, and firms not having ethics programs," said Andrew Felo, assistant professor of accounting at Penn State Great Valley graduate school in suburban Philadelphia.

Using a systems biological analysis of genome-scale data from the model plant Arabidopsis, an international team of researchers identified that the master gene controlling the biological clock is sensitive to nutrient status.
This hypothesis derived from multi-network analysis of Arabidopsis genomic data, and validated experimentally, has shed light on how nutrients affect the molecular networks controlling plant growth and development in response to nutrient sensing.

Scientists have used the world's largest robotic telescope to make the earliest-ever measurement of the optical polarisation* of a Gamma Ray Burst (GRB) just 203 seconds after the start of the cosmic explosion. This finding, which provides new insight into GRB physics, is published in Science today (15th March 2007).
The scientists from Liverpool John Moores University and colleagues in the UK, Italy, France and Slovenia used the Liverpool Telescope on the island of La Palma and its novel new polarimeter, RINGO, to perform the measurement following detection of the burst by NASA's Swift satellite.

NASA's Swift spacecraft. Credit: Spectrum and NASA E/PO, Sonoma State University

Over a span of two decades, warming temperatures have caused annual losses of roughly $5 billion for major food crops, according to a new study by researchers at the Carnegie Institution and Lawrence Livermore National Laboratory.
From 1981-2002, warming reduced the combined production of wheat, corn, and barley—cereal grains that form the foundation of much of the world’s diet—by 40 million metric tons per year.

Humans acquire fears using similar neural processes whether they’ve personally experienced an aversive event or only witnessed it, according to a study by researchers at New York University’s Departments of Psychology. This is the first study examining the brain basis of fears acquired indirectly, through the observation of others. The study shows that the amygdala, which is known to be critical to the acquisition and expression of fears from personal experience, is also involved during the acquisition and expression of fears obtained indirectly through social observation. The findings appear in the most recent issue of the journal Social Cognitive and Affective Neuroscience (SCAN).

Sandia’s huge Z machine, which generates termperatures hottter than the sun, has turned water to ice in nanoseconds. However, don’t expect anything commercial just yet: the ice is hotter than the boiling point of water. "The three phases of water as we know them — cold ice, room temperature liquid, and hot vapor — are actually only a small part of water’s repertory of states," says Sandia researcher Daniel Dolan. "Compressing water customarily heats it. But under extreme compression, it is easier for dense water to enter its solid phase [ice] than maintain the more energetic liquid phase [water]."
Sandia is a National Nuclear Security Administration (NNSA) laboratory.

Over a span of two decades, warming temperatures have caused annual losses of roughly $5 billion for major food crops, according to a new study by researchers at the Carnegie Institution and Lawrence Livermore National Laboratory.
From 1981-2002, warming reduced the combined production of wheat, corn, and barley—cereal grains that form the foundation of much of the world’s diet—by 40 million metric tons per year.

Since the beginning of the industrial age the ocean has absorbed about half of all anthropic(1) carbon dioxide (CO2) emissions into the atmosphere. This has led to an acidification of sea water. Frédéric Gazeau, a scientist at the Netherlands Institute of Ecology, and his colleagues, including Jean-Pierre Gattuso, Director of Research at the Oceanographic laboratory at Villefranche-sur-Mer (CNRS/Université Pierre et Marie Curie) have examined the reaction of oysters and mussels cultivated in Europe to this acidification of the oceans. The results, published in the review Geophysical Research Letters, are beyond doubt.

Some 40 years after the release of the classic science fiction movie Fantastic Voyage, researchers in the NanoRobotics Laboratory of École Polytechnique de Montréal’s Department of Computer Engineering and Institute of Biomedical Engineering have achieved a major technological breakthrough in the field of medical robotics. They have succeeded for the first time in guiding, in vivo and via computer control, a microdevice inside an artery, at a speed of 10 centimetres a second.

USC College computational biologist Peter Calabrese has developed a new model to simulate the evolution of so-called recombination hotspots in the genome.
Published March 5 in the early online edition of the Proceedings of the National Academy of Sciences, the mathematical model and its associated software bring much-needed rigor to evolutionary investigations of how natural selection acts on individual genes, said Calabrese, a research assistant professor of biological sciences.