News Articles

In work that could dramatically boost the capabilities of "lab on a chip" devices, MIT researchers have created a way to use tiny bubbles to mimic the capabilities of a computer.
The team, based at MIT's Center for Bits and Atoms, reports that the bubbles in their microfluidic device can carry on-chip process control information, just like the electronic circuits of a traditional microprocessor, while also performing chemical reactions. The work will appear in the Feb. 9 issue of Science.

MIT researchers have developed a computer chip that runs on microbubbles like these. (Photo courtesy of Manu Prakash)

Although no two brains are alike, they can display a comparable pattern of neural activity when exposed to similar sensory input. Scientists at the Max Planck Institute for Dynamics and Self-Organization in Göttingen have now developed a mathematical method to design networks from neural cells which exhibit a predefined pattern dynamics. The researchers hope that their method will assist them in getting closer to understanding which of the possible network configurations was privileged by evolution -- and why (Physica D: Nonlinear Phenomena, December, 2006).

Different neuronal networks can bear the same pattern of activity -- as shown in this example of a network made of 16 neurons.

For cells that hold so much promise, stem cells' potential has so far gone largely untapped. But new research from Rockefeller University and Howard Hughes Medical Institute scientists now shows that adult stem cells taken from skin can be used to clone mice using a procedure called nuclear transfer. The findings are reported in the Feb. 12 online edition of the Proceedings of the National Academy of Sciences.

Using a technique called nuclear transfer, mice were cloned using adult skin stem cells (right) and a more differentiated type of skin cell (left). The mouse on the right is almost two years old and the mouse on the right is one and a half.

The Scripps Research team, led by neuroscientists Manuel Sanchez-Alavez and Tamas Bartfai, discovered that mice genetically altered to lack a molecule known as the EP3 receptor tend to be more active during their normal sleep cycle and to eat more. In the study, this led to weight increases of up to 30 percent relative to mice with the receptors.
The EP3 receptor is one of four types of receptors for prostaglandin E2 (PGE2), the most important inflammatory mediator that controls a variety of physiological functions including fever, fertility, and blood pressure.

Some breaking news, just in time for Valentine's Day: Researchers have identified something called "sperm competition" that they think has evolved to ensure a genetic future. In sexual reproduction, natural selection is generally thought of as something that happens prior to – and in fact leads to -- the Big Event. This thinking holds, for example, that we are drawn to physical features that tell us our partner is healthy and will give us a fighting chance to carry on our genetic lineage.

Two of Greenland's largest glaciers shrank dramatically and dumped twice as much ice into the sea during a period of less than a year between 2004 and 2005. And then, less than two years later, they returned to near their previous rates of discharge.
The variability over such a short time, reported online Feb. 9 on Science magazine's Science Express, underlines the problem in assuming that glacial melting and sea level rise will necessarily occur at a steady upward trajectory, according to lead author Ian Howat, a post-doctoral researcher with the University of Washington's Applied Physics Laboratory and the University of Colorado's National Snow and Ice Data Center.

A new statistical method of determining genetic traits that influence social interactions among animals may provide for more productive livestock.
Scientists from Purdue University, the Netherlands and England designed mathematical equations based on traits to choose animals that are more congenial in groups, said William Muir, a Purdue Department of Animal Sciences geneticist. The new method is a tool that may contribute both to animal well-being and to securing the world's future food supply, including possibly permitting more animals to be domesticated, Muir said.
The tool makes it possible to design selective breeding programs to effectively reduce competitive interactions in livestock, he said.

New techniques paint clearer picture of amyloid formation associated with protein-based inheritance and neurodegenerative diseases such as mad cow, Alzheimer's
The new findings, which are being published the week of February 12 in an online edition of the Proceedings of the National Academy of Sciences, offer significant insights into normal folding mechanisms as well as those that lead to abnormal amyloid fibril conversion. The new insights may lead to the discovery of novel therapeutic targets for neurodegenerative diseases.
Intriguingly, certain prions and amyloids can play beneficial roles. The subject of the new study, Sup35, enables protein-based inheritance in yeast.

Being a green consumer is hard work, according to new research funded by the Economic and Social Research Council (ESRC). The study highlights a need for more practical help and incentives for green consumers, if we are to achieve a more sustainable society.
The University of Leeds-led study found that consumers who try to live a sustainable lifestyle have difficulty deciding which product to buy. "Consumers find that being green or ethical is a very hard, time consuming, and emotional experience," says Dr William Young.

In side-by-side taste tests, pub-goers agree: “MIT Brew” tastes better than Budweiser — as long as tasters don’t learn beforehand that the secret ingredient is balsamic vinegar.
It sounds more like a fraternity prank than a psychology experiment, but the beer-guzzling participants in a recent study were doing their part for psychology. In this case, helping researchers determine just what it is about consumers’ knowledge of food products that af-fects their taste judgments.

Does Knowledge Of Food Products Affect Taste Judgment?

Fermions tend to avoid each other and cannot "travel" in close proximity. Demonstrated by a team at the Institut d'optique (CNRS/Université Paris 11, Orsay-Palaiseau), this result is described in detail in the January 25, 2007 issue of Nature. It marks a major advance in our understanding of phenomena at a quantum scale.
For many years, the theory of quantum mechanics stipulated that certain particles, the fermions(1), were incapable of "travelling" in close proximity.

Aggressive research currently underway brings hope of dramatic advances in breast cancer management, according to a new review. Published in the March 15, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the review reveals that new approaches in breast cancer imaging, investigations into the timing of chemotherapy, and research on breast cancer vaccines may lead to exciting new nonsurgical tools for the physician treating breast cancer patients. These new tools may significantly alter current screening and treatment paradigms used by surgical oncologists, as well improving the care of patients.
Our understanding of breast cancer has changed since Dr. William Halsted started performing radical mastectomies in the 1880s.